Landiolol for managing atrial fibrillation in intensive care

被引:13
|
作者
Rehberg, Sebastian [1 ]
Joannidis, Michael [2 ]
Whitehouse, Tony [3 ]
Morelli, Andrea [4 ]
机构
[1] Univ Hosp Greifswald, Dept Anaesthesiol, D-17475 Greifswald, Germany
[2] Med Univ Innsbruck, Dept Internal Med, Div Intens Care & Emergency Med, A-6020 Innsbruck, Austria
[3] Univ Hosp Birmingham, Dept Crit Care & Anaesthesia, Birmingham B15 2GW, W Midlands, England
[4] Univ Roma La Sapienza, Italy Policlin Umberto Hosp 1, Dept Anesthesiol & Intens Care Med, Viale Policlin 155, I-00161 Rome, Italy
关键词
Landiolol; Beta-blockers; Atrial fibrillation; Supraventricular arrhythmia; Heart-rate control; Sepsis; Intensive care; BETA-1-SELECTIVE BLOCKER LANDIOLOL; HEART-RATE CONTROL; SEPTIC SHOCK; RAT MODEL; BETA-BLOCK; OUTCOMES; SEPSIS; MANAGEMENT; ESMOLOL; HYDROCHLORIDE;
D O I
10.1093/eurheartj/sux039
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
Landiolol is an injectable ultrashort acting beta-blocker with high beta1 selectivity indicated for heart rate control of atrial fibrillation in the emergency and critical care setting. Accordingly, landiolol is associated with a significantly reduced risk of arterial hypotension and negative inotropic effects. Based on this particular profile along with the clinical experience in Japan for more than a decade landiolol represents a promising agent for the management of elevated heart rate and atrial fibrillation in intensive care patients even with catecholamine requirements. This article provides a review and perspective of landiolol for heart rate control in intensive care patients based on the current literature.
引用
收藏
页码:A15 / A18
页数:4
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