Novel key cytokines in allergy: IL-17, IL-22

被引:1
|
作者
Eyerich, S. [2 ]
Traidl-Hoffmann, C. [1 ,2 ]
Behrendt, H. [2 ]
Cavani, A. [3 ]
Schmidt-Weber, C. B. [2 ]
Ring, J. [1 ]
Eyerich, K. [1 ]
机构
[1] Tech Univ Munich, Klin & Poliklin Dermatol & Allergol Biederstein, D-80802 Munich, Germany
[2] Helmholtz Zentrum Munchen, Munich, Germany
[3] Ist Dermopat DellImmacolata, Immunol Lab, Rome, Italy
关键词
immunology; T cell; cytokine; IL-17; IL-22; DELTA-T-CELLS; ARYL-HYDROCARBON RECEPTOR; ROR-GAMMA-T; TH17; CELLS; INTERLEUKIN; 22; T-H-17; T(H)17 CELLS; HOST-DEFENSE; LUNG INJURY; IFN-GAMMA;
D O I
10.5414/ALP34344
中图分类号
R392 [医学免疫学];
学科分类号
100102 ;
摘要
Novel key cytokines in allergy: IL-17, IL-22 The biology of the T cell cytokines Interleukin (IL-)17 and IL-22 has been a main focus in the field of clinical immunology in the last decade. This intensive interest in both cytokines resulted in almost 5,000 scientific publications (www.pubmed.com) dealing with the molecular structure, extra- and intracellular signaling pathways, specific transcription factors and the function of IL-17 and IL-22. This review article highlights the main findings concerning IL-17 and IL-22 in the last years.
引用
收藏
页码:344 / 349
页数:6
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