Invasive tests for Helicobacter pylori in children

被引：2

作者：

Huynh, HQ ^{[1
]}

机构：

[1] Univ Alberta, Stollery Childrens Hosp, Dept Pediat, Div Pediat Gastroenterol & Nutr, Edmonton, AB, Canada

来源：

CANADIAN JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY | 2005年 / 19卷 / 07期

关键词：

children; endoscopy; H pylori; histology; invasive; molecular diagnostics;

D O I：

10.1155/2005/514280

中图分类号：

R57 [消化系及腹部疾病];

学科分类号：

摘要：

One of the primary indications for upper gastrointestinal (GI) endoscopy in children is the presence of persistent and severe upper abdominal symptoms. Upper GI endoscopies are per-formed to allow the physician to confirm or rule out upper GI pathology. Additionally, upper GI endoscopies with mucosal biopsies are the gold standard for the diagnosis of Helicobacter pylori infection and its complications in children. The gastric biopsies can be used for the rapid urease test, histological examination and bacterial culture to determine antibiotic sensitivity. DNA extracted in these biopsies can also be subjected to genotyping using molecular methods to determine the presence of H pylori infection, antibiotic resistance mutations and H pylori virulence factors.

引用

页码：429 / 432

页数：4

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