Carboxylated magnetic polymer nanolatexes: Preparation, characterization and biomedical applications

被引:41
作者
Zheng, WM [1 ]
Gao, F [1 ]
Gu, HC [1 ]
机构
[1] Shanghai Jiao Tong Univ, Engn Res Ctr Nano Sci & Technol, Shanghai 200030, Peoples R China
关键词
carboxyl groups; magnetic polymer latex; miniemulsion polymerization; ACPA; antibody; covalent coupling;
D O I
10.1016/j.jmmm.2005.01.082
中图分类号
T [工业技术];
学科分类号
08 ;
摘要
Carboxylated magnetic polymer nanolatexes were prepared by miniemulsion polymerization using 4,4'-azobis (4-cyanopentanoic acid) (ACPA) as initiator, which provided carboxyl end groups on the latex surface directly. The colloidal stability and the magnetic properties showed that these resulting carboxylated magnetic polymer nanolatexes were applicable in biomedical separation, which was performed by covalent coupling of activated antibody. (c) 2005 Elsevier B.V. All rights reserved.
引用
收藏
页码:199 / 205
页数:7
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