Ultrasensitive nanosensor based on gold nanoparticles to detect vascular endothelial growth factor (VEGF)

被引：0
|
作者：
Oliveira, J. P. [1 ]
Arruda, R. P. [1 ]
Keijok, W. [1 ]
Cicilini, M. A. [2 ]
Nogueira, B., V [1 ]
Guimaraes, M. C. C. [1 ]
Prado, A. R. [3 ,4 ]
Ribeiro, M. R. N. [3 ]
Pontes, M. J. [3 ]
机构：
[1] Univ Fed Espirito Santo, Dept Morfol, Vitoria, Brazil
[2] Univ Fed Espirito Santo, Dept Ciencias Fisiol, Vitoria, Brazil
[3] Univ Fed Espirito Santo, Posgrad Engn Eletr, Vitoria, Brazil
[4] Inst Fed Espirito Santo, Serra, Brazil
来源：
2015 IEEE 15TH INTERNATIONAL CONFERENCE ON NANOTECHNOLOGY (IEEE-NANO) | 2015年
关键词：
gold nanoparticles; vascular endothelial growth factor; plasmon resonance; biosensors; RECOGNITION; RECEPTORS; CANCER;
D O I：
暂无
中图分类号：
TM [电工技术]; TN [电子技术、通信技术];
学科分类号：
0808 ; 0809 ;
摘要：
We report on the use of new biosensor that enable a surface Plasmon resonance (SPR) sensor to detec VEGF in tissue extracts and cell lysates. This sensor consist of gold nanoparticles functionalized with antibodies anti-VEGF. To analyze the optical properties and their sensing ability was held optical absorption experiments in band plasmon resonance. We demonstrate that this approach makes it possible for the SPR biosensor to detect VEGF in tissues at low concentrations.
引用
收藏
页码：1049 / 1053
页数：5
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