Synthesis of hydroxyapatite crystals using titanium oxide electrospun nanofibers

被引:25
作者
C., Remant Bahadur K. [2 ]
Kim, Chul Ki [1 ]
Khil, Myung Seob [3 ]
Kim, Hak Yong [1 ]
Kim, Ick Soo [4 ]
机构
[1] Chonbuk Natl Univ, Dept Text Engn, Jeonju 561756, South Korea
[2] Chonbuk Natl Univ, Dept Bionanosyst Engn, Jeonju 561756, South Korea
[3] Chonbuk Natl Univ, Ctr Healthcare Technol Dev, Jeonju 561756, South Korea
[4] Shinshu Univ, Fac Text Sci & Technol, Ueda, Nagano 3868567, Japan
来源
MATERIALS SCIENCE & ENGINEERING C-BIOMIMETIC AND SUPRAMOLECULAR SYSTEMS | 2008年 / 28卷 / 01期
基金
新加坡国家研究基金会;
关键词
nanofibers; biomimetic; electrospinning; biomaterials; metal-ceramic nanocomposite;
D O I
10.1016/j.msec.2006.11.007
中图分类号
T [工业技术];
学科分类号
08 ;
摘要
Metal-ceramic nanocomposites have a special interest for biomedical applications such as in dental and bone implants. One interesting possibility to control the size of these materials is their fabrication on electrospun nanofibers. In this communication, we reported the use of bio-activated titanium oxide electrospun nanofibers as a template for the synthesis of hydroxyapatite: (HAp) [Ca-10(PO4)(6)(OH)(2)] crystals. Titanium oxide (TiO2) nanofibers were fabricated using a viscous solution of titanium isopropoxide (TiP)/poly(vinyl acetate) (PVAc) via electrospinning and then chemically treated with NaOH followed by diluted HC1 to explore the possibility of enhancing the bioactivity. Thus obtained nanofibers were employed for the simulated body fluid (SBF) mediated biomimatic synthesis of HAp crystals. The composites were characterized by different physico-chemical (FT-IR, XPS, XRD, SEM, and EDX) techniques. Results showed that the activated TiO2 nanofibers served as an effective template for the assembly of plate like hydroxyapatite crystals. (C) 2006 Elsevier B.V. All rights reserved.
引用
收藏
页码:70 / 74
页数:5
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