Upconverting luminescent nanoparticles for use in bioconjugation and bioimaging

被引：397

作者：

Mader, Heike S. ^{[1
]}

Kele, Peter ^{[1
]}

Saleh, Sayed M. ^{[1
]}

Wolfbeis, Otto S. ^{[1
]}

机构：

[1] Univ Regensburg, Inst Analyt Chem Chemo & Biosensors, D-93040 Regensburg, Germany

来源：

CURRENT OPINION IN CHEMICAL BIOLOGY | 2010年 / 14卷 / 05期

关键词：

UP-CONVERSION LUMINESCENCE; NAYF4; NANOCRYSTALS; FLUORESCENCE; NANOPHOSPHORS; CELLS; LAF3; NANOCOMPOSITES; NANOMATERIALS; NAYF4-YB; ER; STRATEGY;

D O I：

10.1016/j.cbpa.2010.08.014

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

Upconverting luminescent nanoparticles (UCNPs) display the unique property of emitting visible light following photoexcitation with near-infrared laser light. This results in features such as virtually zero autofluorescence of (biological) matter and easy separation of the emission peaks from stray light. Other features include rather narrow emission bands, very high chemical stability, the lack of bleaching, and the absence of blinking effects. This article reviews the work performed in the past few years with UCNPs in terms of surface modifications, bioconjugation, and optical (cellular) imaging.

引用

页码：582 / 596

页数：15

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