Aquaporin 4 and glymphatic flow have central roles in brain fluid homeostasis

被引:61
作者
Salman, Mootaz M. [1 ,2 ]
Kitchen, Philip [3 ]
Iliff, Jeffrey J. [4 ,5 ,6 ]
Bill, Roslyn M. [3 ]
机构
[1] Univ Oxford, Dept Physiol Anat & Genet, Oxford, England
[2] Univ Oxford, Oxford Parkinsons Dis Ctr, Oxford, England
[3] Aston Univ, Sch Biosci, Coll Hlth & Life Sci, Birmingham, W Midlands, England
[4] Univ Washington, Sch Med, Dept Psychiat & Behav Sci, Seattle, WA 98195 USA
[5] Univ Washington, Sch Med, Dept Neurol, Seattle, WA 98195 USA
[6] VA Puget Sound Hlth Care Syst, VISN 20 Mental Illness Res Educ & Clin Ctr, Seattle, WA 98108 USA
基金
英国生物技术与生命科学研究理事会;
关键词
D O I
10.1038/s41583-021-00514-z
中图分类号
Q189 [神经科学];
学科分类号
071006 ;
摘要
引用
收藏
页码:650 / 651
页数:2
相关论文
共 9 条
  • [1] Direct imaging of glymphatic transport using H217O MRI
    Alshuhri, Mohammed S.
    Gallagher, Lindsay
    Work, Lorraine M.
    Holmes, William M.
    [J]. JCI INSIGHT, 2021, 6 (10)
  • [2] Aquaporin-4 Surface Trafficking Regulates Astrocytic Process Motility and Synaptic Activity in Health and Autoimmune Disease
    Ciappelloni, Silvia
    Bouchet, Delphine
    Dubourdieu, Nadege
    Boue-Grabot, Eric
    Kellermayer, Blanka
    Manso, Constance
    Marignier, Romain
    Oliet, Stephane H. R.
    Tourdias, Thomas
    Groc, Laurent
    [J]. CELL REPORTS, 2019, 27 (13): : 3860 - +
  • [3] Targeting Aquaporin-4 Subcellular Localization to Treat Central Nervous System Edema
    Kitchen, Philip
    Salman, Mootaz M.
    Halsey, Andrea M.
    Clarke-Bland, Charlotte
    MacDonald, Justin A.
    Ishida, Hiroaki
    Vogel, Hans J.
    Almutiri, Sharif
    Logan, Ann
    Kreida, Stefan
    Al-Jubair, Tamim
    Missel, Julie Winkel
    Gourdon, Pontus
    Tomroth-Horsefield, Susanna
    Conner, Matthew T.
    Ahmed, Zubair
    Conner, Alex C.
    Bill, Roslyn M.
    [J]. CELL, 2020, 181 (04) : 784 - +
  • [4] AQP4e-Based Orthogonal Arrays Regulate Rapid Cell Volume Changes in Astrocytes
    Lisjak, Marjeta
    Potokar, Maja
    Rituper, Bostjan
    Jorgacevski, Jernej
    Zorec, Robert
    [J]. JOURNAL OF NEUROSCIENCE, 2017, 37 (44) : 10748 - 10756
  • [5] Molecular mechanisms of brain water transport
    MacAulay, Nanna
    [J]. NATURE REVIEWS NEUROSCIENCE, 2021, 22 (06) : 326 - 344
  • [6] Cerebrospinal fluid influx drives acute ischemic tissue swelling
    Mestre, Humberto
    Du, Ting
    Sweeney, Amanda M.
    Liu, Guojun
    Samson, Andrew J.
    Peng, Weiguo
    Mortensen, Kristian Nygaard
    Staeger, Frederik Filip
    Bork, Peter A. R.
    Bashford, Logan
    Toro, Edna R.
    Tithof, Jeffrey
    Kelley, Douglas H.
    Thomas, John H.
    Hjorth, Poul G.
    Martens, Erik A.
    Mehta, Rupal I.
    Solis, Orestes
    Blinder, Pablo
    Kleinfeld, David
    Hirase, Hajime
    Mori, Yuki
    Nedergaard, Maiken
    [J]. SCIENCE, 2020, 367 (6483) : 1211 - +
  • [7] Aquaporin-4-dependent glymphatic solute transport in the rodent brain
    Mestre, Humberto
    Hablitz, Lauren M.
    Xavier, Anna L. R.
    Feng, Weixi
    Zou, Wenyan
    Pu, Tinglin
    Monai, Hiromu
    Murlidharan, Giridhar
    Rivera, Ruth M. Castellanos
    Simon, Matthew J.
    Pike, Martin M.
    Pla, Virginia
    Du, Ting
    Kress, Benjamin T.
    Wang, Xiaowen
    Plog, Benjamin A.
    Thrane, Alexander S.
    Lundgaard, Iben
    Abe, Yoichiro
    Yasui, Masato
    Thomas, John H.
    Xiao, Ming
    Hirase, Hajime
    Asokan, Aravind
    Iliff, Jeffrey J.
    Nedergaard, Maiken
    [J]. ELIFE, 2018, 7
  • [8] Smith AJ, 2017, ELIFE, V6, DOI [10.7554/elife.27679, 10.7554/eLife.27679]
  • [9] Lack of aquaporin-4 water transport inhibition by antiepileptics and arylsulfonamides
    Yang, Baoxue
    Zhang, Hua
    Verkman, A. S.
    [J]. BIOORGANIC & MEDICINAL CHEMISTRY, 2008, 16 (15) : 7489 - 7493