A water-soluble β-cyclodextrin derivative possessing a fullerene tether as an efficient photodriven DNA-cleavage reagent

被引：39

作者：

Liu, Y ^{[1
]}

Zhao, YL ^{[1
]}

Chen, Y ^{[1
]}

Liang, P ^{[1
]}

Li, L ^{[1
]}

机构：

[1] Nankai Univ, Dept Chem, State Key Lab ElementoOrgan Chem, Tianjin 300071, Peoples R China

来源：

TETRAHEDRON LETTERS | 2005年 / 46卷 / 14期

基金：

中国国家自然科学基金;

关键词：

cyclodextrin; Diels-Alder reaction; DNA-cleavage; fullerene;

D O I：

10.1016/j.tetlet.2005.01.181

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

A simple synthetic route for a water-soluble cyclodextrin-fullerene conjugate based on the Diels-Alder reaction between anthryl-cyclodextrin and fullerene has been presented. Aided by the fascinating biochemical functions of fullerene, the resultant cyclodextrin-C-60 conjugate displays a satisfactory DNA-cleavage ability under the visible-light irradiation. (c) 2005 Elsevier Ltd. All rights reserved.

引用

页码：2507 / 2511

页数：5

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