Dendrimers: a new class of nanoscopic containers and delivery devices

被引：332
作者：
Aulenta, F
Hayes, W [1 ]
Rannard, S
机构：
[1] Univ Reading, Sch Chem, Reading RG6 6AH, Berks, England
[2] Unilever Res Labs, Wirral CH63 3JW, Merseyside, England
来源：
EUROPEAN POLYMER JOURNAL | 2003年 / 39卷 / 09期
关键词：
dendrimer; hyperbranched polymer; drug delivery devices; host-guest chemistries;
D O I：
10.1016/S0014-3057(03)00100-9
中图分类号：
O63 [高分子化学（高聚物）];
学科分类号：
070305 ; 080501 ; 081704 ;
摘要：
Dendrimers and hyperbranched polymers are a relatively new class of materials with unique molecular architectures and dimensions in comparison to traditional linear polymers. This review details recent notable advances in the application of these new polymers in terms of the development of new polymeric delivery systems. Although comparatively young, the developing field of hyperbranched drug delivery devices is a rapidly maturing area and the key discoveries in drug-conjugate systems amongst others are highlighted. As a consequence of their ideal hyperbranched architectures, the utilisation of host-guest chemistries in dendrimers has been included within the scope of this review. (C) 2003 Elsevier Ltd. All rights reserved.
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页码：1741 / 1771
页数：31
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