Fine-scale genetic diversity among Burkholderia pseudomallei soil isolates in northeast Thailand

被引:19
作者
U'Ren, Jana M.
Hornstra, Heidie
Pearson, Talima
Schupp, James M.
Leadem, Benjamin
Georgia, Shalamar
Sermswan, Rasana W.
Keim, Paul
机构
[1] No Arizona Univ, Ctr Microbiol Genet & Genom, Flagstaff, AZ 86011 USA
[2] Khon Kaen Univ, Fac Med, Dept Biochem, Khon Kaen, Thailand
关键词
D O I
10.1128/AEM.00986-07
中图分类号
Q81 [生物工程学(生物技术)]; Q93 [微生物学];
学科分类号
071005 ; 0836 ; 090102 ; 100705 ;
摘要
Burkholderia pseudomallei soil isolates from northeast Thailand were genotyped using multiple-locus variable-number tandem repeat (VNTR) analysis (MLVA) and multilocus sequence typing (MLST). MLVA identified 19 genotypes within three clades, while MLST revealed two genotypes. These close genetic relationships imply a recent colonization followed by localized expansion, similar to what occurs in an outbreak situation.
引用
收藏
页码:6678 / 6681
页数:4
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