Nocturnal secretion of melatonin (MLT) in patients with duodenal ulcer disease (DUD)

被引：0
|
作者：
Klupinska, G [1 ]
Malkowski, B [1 ]
Maziarz, Z [1 ]
Chojnacki, J [1 ]
Zajac, A [1 ]
Tryniszewski, W [1 ]
机构：
[1] Med Univ Lodz, Dept Gastroenterol & Internal Dis, Dept Diagnost & Therapy Radiol & Nucl Med, PL-90131 Lodz, Poland
来源：
PROCEEDINGS OF THE 12TH INTERNATIONAL CONGRESS OF ENDOCRINOLOGY | 2004年
关键词：
D O I：
暂无
中图分类号：
R5 [内科学];
学科分类号：
1002 ; 100201 ;
摘要：
Melatonin (MLT) is thought to have gastroprotective properties particularly by stimulating bicarbonate secretion and antioxidative activity. In own study MLT nocturnal secretion (10 pm, 12 pm, 2 am and 4 am) was investigated in 39 patients with duodenal ulcer disease (DUD) within the period of autumn exacerbation of the disease and in 24 healthy subjects. H. pylori infection was excluded. Melatonin was determined in blood plasma with radioimmunological method. Lower MLT secretion was observed in DUD patients as compared with healthy subjects. The most significant differences were found at 2 am - 24,48 +/- 8,78 and 44.05 +/- 10,22 pg/ml, respectively (p < 0,01). These observations indicate that MLT may play an important role in DUD pathogenesis.
引用
收藏
页码：451 / 454
页数：4
相关论文
共 50 条
  • [21] THE INHIBITION OF NOCTURNAL GASTRIC-ACID SECRETION BY OMEPRAZOLE IN PATIENTS WITH DUODENAL-ULCER
    SHEARMAN, DJC
    BUCKLE, PJ
    HETZEL, DJ
    SCANDINAVIAN JOURNAL OF GASTROENTEROLOGY, 1986, 21 : 145 - 146
  • [22] NOCTURNAL GASTRIC SECRETION .2. STUDIES ON NORMAL SUBJECTS AND PATIENTS WITH DUODENAL ULCER
    SANDWEISS, DJ
    FRIEDMAN, MHF
    SUGARMAN, MH
    PODOLSKY, HM
    GASTROENTEROLOGY, 1946, 7 (01) : 38 - 54
  • [23] INHIBITION OF NOCTURNAL GASTRIC-SECRETION BY SK AND F 93479 IN PATIENTS WITH DUODENAL-ULCER
    HETZEL, DJ
    BARTHOLOMEUSZ, FDL
    SHEARMAN, DJC
    IRCS MEDICAL SCIENCE-BIOCHEMISTRY, 1982, 10 (10): : 800 - 801
  • [24] NOCTURNAL GASTRIC-SECRETION IN DUODENAL-ULCER PATIENTS AND HEALTHY CONTROLS - RANGES AND REPRODUCIBILITY
    BOYD, EJS
    WORMSLEY, KG
    SCANDINAVIAN JOURNAL OF GASTROENTEROLOGY, 1992, 27 (01) : 44 - 46
  • [25] INHIBITION OF NOCTURNAL ACID SECRETION IN DUODENAL-ULCER BY ORAL METIAMIDE
    WILLIAMS, JG
    MILTONTH.GJ
    JENKINS, DJA
    MISIEWICZ, JJ
    GUT, 1974, 15 (04) : 337 - 337
  • [26] NOCTURNAL MELATONIN SECRETION IN DEPRESSED-PATIENTS
    JARRETT, DB
    BOWEN, WC
    MIEWALD, JM
    KUPFER, DJ
    GREENHOUSE, JB
    JOURNAL OF NEURAL TRANSMISSION, 1986, : 487 - 487
  • [27] H-pylori negative ['IDIOPATHIC'] duodenal ulcer disease [DUD] in children is a different disease from Hp positive DUD
    Hassall, E
    Dohil, R
    Dimmick, JE
    GASTROENTEROLOGY, 2002, 122 (04) : A548 - A548
  • [28] SALIVARY SECRETION IN DUODENAL-ULCER DISEASE
    BLUM, AL
    ACTA HEPATO-GASTROENTEROLOGICA, 1973, 20 (02): : 174 - 174
  • [29] SALIVARY SECRETION IN DUODENAL-ULCER DISEASE
    BLUM, AL
    WOODALL, JW
    GUT, 1972, 13 (09) : 713 - &
  • [30] Abnormal melatonin secretion rhythm and nocturnal polyuria in patients with Parkinson's disease
    Uchiyama, T.
    Yamamoto, T.
    Suzuki, K.
    Kadowaki, T.
    Numao, A.
    Fujita, H.
    Watanabe, Y.
    Matsubara, T.
    Miyamoto, M.
    Kaga, K.
    Yamanishi, T.
    Sakakibara, R.
    Kuwabara, S.
    Hirata, K.
    MOVEMENT DISORDERS, 2017, 32
12345