Total synthesis of (+)-epopromycin B and its analogues - studies on the inhibition of cellulose biosynthesis

被引：10

作者：

Dobler, MR ^{[1
]}

机构：

[1] Novartis Crop Protect AG, Lead Discovery, CH-4002 Basel, Switzerland

来源：

TETRAHEDRON LETTERS | 2001年 / 42卷 / 02期

关键词：

D O I：

10.1016/S0040-4039(00)01944-4

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

The described inhibition of the cellulose biosynthesis by epopromycin B prompted us to establish a short and efficient synthesis of the natural product, suitable for accessing a broad range of unnatural analogues in a multiparallel fashion. During the course of our synthesis the absolute configuration of (+)-epopromycin B could be determined. (C) 2000 Elsevier Science Ltd. All rights reserved.

引用

页码：215 / 218

页数：4

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