Protein-carbohydrate interactions during fertilization

被引:0
|
作者
Sinowatz, F [1 ]
Plendl, J [1 ]
Kölle, S [1 ]
机构
[1] Univ Munich, Inst Tieranat 2, Lehrstuhl Tieranat 2, D-80539 Munich, Germany
来源
ACTA ANATOMICA | 1998年 / 161卷 / 1-4期
关键词
protein; carbohydrate; fertilization; zona pellucida; sperm receptor;
D O I
暂无
中图分类号
R602 [外科病理学、解剖学]; R32 [人体形态学];
学科分类号
100101 ;
摘要
Interaction between gametes during fertilization is at least in part regulated by carbohydrate moieties of the zona pellucida (ZP) and carbohydrate binding proteins of the sperm surface. This review focuses on the protein-carbohydrate interactions during the primary binding of the sperm to the ZP in different species. Synthesis, structure and composition of the ZP an summarized. The functional significance of carbohydrate residues of the ZP as sperm receptor is discussed. Sperm surface proteins known to have specific ZP and carbohydrate-binding sites including the mouse beta 1,4-galactosyltransferase and sp56, the rabbit protein Sp17, a human mannose-binding protein and several members of the sperm-adhesin family are presented.
引用
收藏
页码:196 / 205
页数:10
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