Real-Time Analysis of Mucosal Flora in Patients with Inflammatory Bowel Disease in India

被引:102
作者
Verma, Ravi [1 ]
Verma, Anil Kumar [1 ]
Ahuja, Vineet [2 ]
Paul, Jaishree [1 ]
机构
[1] Jawaharlal Nehru Univ, Sch Life Sci, New Delhi 110067, India
[2] All India Inst Med Sci, Dept Gastroenterol, New Delhi, India
关键词
ULCERATIVE-COLITIS PATIENTS; SULFATE-REDUCING BACTERIA; CROHNS-DISEASE; MICROBIOTA; COLON; MICROFLORA; HEALTH; IBD;
D O I
10.1128/JCM.01360-10
中图分类号
Q93 [微生物学];
学科分类号
071005 ; 100705 ;
摘要
Mucosa-associated bacterial flora from control individuals and inflammatory bowel disease (IBD) patients were evaluated by real-time analysis using 16S rRNA-based genus-specific primers. Our data show a clear delineation in concentration of bacteria between the predominating and subdominating genera under disease conditions, indicating that the subsets of bacteria participating in the pathogenesis of ulcerative colitis (UC) and Crohn's disease (CD) are likely to be different.
引用
收藏
页码:4279 / 4282
页数:4
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