Determination of Phase Equilibrium (Solid-Liquid-Gas) in Poly-(ε-caprolactone)-Carbon Dioxide Systems

被引：33

作者：

de Paz, Esther ^{[1
]}

Martin, Angel ^{[1
]}

Rodriguez-Rojo, Soraya ^{[1
]}

Herreras, Javier ^{[1
]}

Jose Cocero, Maria ^{[1
]}

机构：

[1] Univ Valladolid, High Pressure Proc Grp, Dept Chem Engn & Environm Technol, E-47011 Valladolid, Spain

来源：

JOURNAL OF CHEMICAL AND ENGINEERING DATA | 2010年 / 55卷 / 08期

关键词：

EQUATION-OF-STATE; CARBON-DIOXIDE; SUPERCRITICAL CO2; RELEASE PROFILES; POLYCAPROLACTONE; MICROSPHERES; SOLUBILITY; MORPHOLOGY; BEHAVIOR; SOLVENT;

D O I：

10.1021/je900997t

中图分类号：

O414.1 [热力学];

学科分类号：

摘要：

Solid-liquid-gas equilibrium of poly-(epsilon-caprolactone)-carbon dioxide systems at high pressure has been determined by visual determination of the first melting point using a static apparatus. Measurements have been performed with poly-(epsilon-caprolactones) of three different molecular weights: 4000 g.mol(-1), 10 000 g . mol(-1), and 25 000 g . mol(-1). The determined SLG equilibrium lines show a temperature maximum at low pressures (0.5 Pa < P < 1.6 MPa) and a temperature minimum at moderate pressures (8 MPa < P < 10 MPa). The maximum reduction of melting temperature ranges from (12.5 to 16.0) K depending on the molecular weight of the polymer. A thermodynamic model based on the PC-SAFT equation of state has been developed to describe experimental data.

引用

页码：2781 / 2785

页数：5

共 23 条

[1] Biodegradable microspheres of novel segmented poly(ether-ester-amide)s based on poly(ε-caprolactone) for the delivery of bioactive compounds [J].