In-vitro investigation for blood flow characteristics in stenotic right coronary artery

被引:0
作者
Park, S. M. [1 ]
Min, Y. U. [1 ]
Kang, M. J. [2 ]
Ji, H. S. [3 ]
Kim, K. C. [3 ]
机构
[1] Pusan Natl Univ, Grad Sch Mech Engn, Pusan 609735, South Korea
[2] Seoul Cent Technol Appraisal Inst, KIBO Technol Fund, Seoul, South Korea
[3] Pusan Natl Univ, Sch Mech Engn, Pusan, South Korea
来源
FOURTH INTERNATIONAL CONFERENCE ON EXPERIMENTAL MECHANICS | 2010年 / 7522卷
基金
新加坡国家研究基金会;
关键词
Cardiovascular Disease; Blood Flow; Right Coronary Artery (RCA); Stenosis; Micro-Particle Image Velocimetry; Computational Fluid Dynamics; Newtonian; Non-Newtonian; VISCOSITY;
D O I
10.1117/12.851452
中图分类号
O3 [力学];
学科分类号
08 ; 0801 ;
摘要
It is very important to investigate hemodynamic and hemorheologic features of blood flow from fluid mechanical point of view because they play major roles in understanding the pathogenesis on cardiovascular disorders. Generally, hemorheologic characteristics of blood flow near the vessel wall are well-known as the most important factor in thrombosis generation according to several hypotheses. To investigate the hemodynamic and hemorheological features related to circulatory diseases, in-vitro experiments were carried out using Micro-PIV technique. Numerical simulation methods using conventional CFD codes were also used to compare with experimental results. The vessel models with stenotic lesion and clinical stent implantation were made of PDMS channel based on Right Coronary Artery (RCA) from clinical angiogram for the patient with stenotic lesion. The hemodynamic and hemorheologic behaviors for control volume near stenotic lesion were evaluated by velocity profiles.
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页数:10
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