Anthelmintic effect of Eucalyptus staigeriana essential oil against goat gastrointestinal nematodes

被引:88
作者
Macedo, Iara T. F. [1 ]
Bevilaqua, Claudia M. L. [1 ]
de Oliveira, Lorena M. B. [1 ]
Camurca-Vasconcelos, Ana L. F. [1 ]
Vieira, Luiz da S. [1 ]
Oliveira, Fabricio R. [1 ]
Queiroz-Junior, Eudson M. [1 ]
Tome, Adriana da R. [1 ]
Nascimento, Nilberto R. F. [1 ]
机构
[1] Univ Estadual Ceara, Programa Pos Grad Ciencias Vet, FAVET, BR-60740000 Fortaleza, Ceara, Brazil
关键词
Phytotherapy; Toxicity; Anthelmintic; In vivo; In vitro; IN-VITRO; LARVICIDAL ACTIVITY; RESISTANCE; SHEEP; TOXICITY; EXTRACTS; PLANTS; TESTS; LEMON;
D O I
10.1016/j.vetpar.2010.06.004
中图分类号
R38 [医学寄生虫学]; Q [生物科学];
学科分类号
07 ; 0710 ; 09 ; 100103 ;
摘要
The aim of this study was to evaluate the anthelmintic efficacy of Eucalyptus staigeriana essential oil (EsEO). The in vitro effects of EsEO were determined through the egg hatching test and the inhibition of larval development of Haemonchus contortus. The oil was subjected to acute and subacute toxicity rodents. The in vivo effects were determined through fecal egg count reduction test in goats. 1.35 and 5.4 mg ml(-1) EsEO inhibited 99.27 and 99.20% H. contortus egg hatching and larval development. In subacute toxicity of EsEO, all parameters were found to be in the normal range, and histopathological analysis of organs did not present alterations. EsEO efficacy against goat gastrointestinal nematodes was 76.57% at 15th day after treatment. E. staigeriana essential oil showed in vitro and in vivo anthelmintic activity. (C) 2010 Elsevier B.V. All rights reserved.
引用
收藏
页码:93 / 98
页数:6
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