Synthesis of Symmetrical and Unsymmetrical 1,4-Dithiins by Rhodium-Catalyzed Sulfur Addition Reaction to Alkynes

被引：11

作者：

Arisawa, Mieko ^{[1
]}

Ichikawa, Takuya ^{[1
]}

Tanii, Saori ^{[1
]}

Yamaguchi, Masahiko ^{[1
]}

机构：

[1] Tohoku Univ, Grad Sch Pharmaceut Sci, Dept Organ Chem, 6-3 Aoba, Sendai, Miyagi 9808578, Japan

来源：

SYNTHESIS-STUTTGART | 2016年 / 48卷 / 18期

关键词：

sulfur; 1,4-dithiins; rhodium; addition reaction; alkynes; CONTAINING POLYMERS; ELEMENTAL SULFUR; THIANTHRENE; COMPLEXES; PLATINUM(II); INHIBITOR; SELENIUM; LIGANDS; ALKENES; KINASE;

D O I：

10.1055/s-0035-1561452

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

A convenient synthetic method for 1,4-dithiins was developed using sulfur and alkynes. A rhodium complex catalyzes the addition reaction of sulfur with cyclic alkynes giving the corresponding symmetrical 1,4-dithiines under reflux conditions in 2-butanone. Unsymmetrical 1,4-dithiins are synthesized by the reaction of sulfur with dialkyl acetylenedicarboxylates in the presence of cyclic alkynes or vinyl ethers.

引用

页码：3107 / 3119

页数：13

共 38 条

[1] Thermal and photochemical 1,3-dipolar cycloaddition of a sulfine (Fluorenethione S-oxide) to the strained triple bond of cyclooctyne [J].