Evidence-based review: Quality of life following head and neck intensity-modulated radiotherapy

被引：44
作者：
Scott-Brown, Martin [2 ]
Miah, Aisha [1 ]
Harrington, Kevin [1 ,3 ]
Nutting, Chris [1 ]
机构：
[1] Royal Marsden Hosp, Head & Neck Unit, London SW3 6JJ, England
[2] Univ Oxford, Gray Inst Radiat Oncol & Biol, Oxford OX1 2JD, England
[3] Inst Canc Res, London SW3 6JB, England
来源：
RADIOTHERAPY AND ONCOLOGY | 2010年 / 97卷 / 02期
关键词：
Head and neck cancer; Intensity-modulated radiotherapy; Quality of life; STAGE NASOPHARYNGEAL CARCINOMA; PAROTID-GLAND FUNCTION; CANCER RECEIVING RADIOTHERAPY; CONVENTIONAL RADIOTHERAPY; RADIATION-THERAPY; CONFORMAL RADIOTHERAPY; SALIVARY FUNCTION; INITIAL REPORT; XEROSTOMIA; IMRT;
D O I：
10.1016/j.radonc.2010.08.004
中图分类号：
R73 [肿瘤学];
学科分类号：
100214 ;
摘要：
Inverse planned Intensity modulated radiotherapy (IMRT) can minimize the dose to normal structures and therefore can reduce long-term radiotherapy-related morbidity and may improve patients' long-term quality of life. Despite overwhelming evidence that IMRT can reduce late functional deficits in patients with head and neck cancer, treated with radiotherapy, a review of the published literature production conflicting results with regard to quality of life outcomes. Following a critical appraisal of the literature, reasons for the discrepant outcomes are proposed. (C) 2010 Elsevier Ireland Ltd. All rights reserved. Radiotherapy and Oncology 97 (2010) 249-257
引用
收藏
页码：249 / 257
页数：9
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