Synthesis and application of some: New thienopyrimidine derivatives as antimicrobial agents

被引：41
|
作者：
Hozien, ZA
Atta, FM
Hassan, KM
AbdelWahab, AA
Ahmed, SA
机构：
[1] Department of Chemistry, Faculty of Science, Assiut University, Assiut
来源：
SYNTHETIC COMMUNICATIONS | 1996年 / 26卷 / 20期
关键词：
D O I：
10.1080/00397919608003791
中图分类号：
O62 [有机化学];
学科分类号：
070303 ; 081704 ;
摘要：
The paper describes the synthesis of new ring system 5-phenylthieno[2,3-d]pyrimidine-4(3H)one (2) Chlorination of (2) with PCl5, POCl3 gave the corresponding 4-chloro derivative (4). Several derivatives of the latter compound have been synthesised and tested for antimicrobial activity.
引用
收藏
页码：3733 / 3755
页数：23
相关论文
共 50 条
  • [41] Synthesis and Reactions of Some New Quinazoline Derivatives for In Vitro Evaluation as Anticancer and Antimicrobial Agents
    Gouhar, Rasha S.
    Kamel, Mohsen M.
    JOURNAL OF HETEROCYCLIC CHEMISTRY, 2018, 55 (09) : 2082 - 2089
  • [42] Synthesis of some new imidazole-2-thiols and their derivatives as potent antimicrobial agents
    Dhawas, Amol K.
    Thakare, Suresh S.
    INDIAN JOURNAL OF CHEMISTRY SECTION B-ORGANIC CHEMISTRY INCLUDING MEDICINAL CHEMISTRY, 2014, 53 (05): : 642 - 646
  • [43] Evaluation of some new synthesis benzothiazole and benzimidazole derivatives as potential antimicrobial and anticancer agents
    Abd Elaziz, Amani Abd Elrazig Salman
    Farag, Ahmed M.
    Alagib, Ishraga Izzeldin Abdelrahim
    Abdallah, Emad M.
    Mohammed, Nawadir Eltieb Abdlla
    INTERNATIONAL JOURNAL OF ADVANCED AND APPLIED SCIENCES, 2020, 7 (02): : 69 - 77
  • [44] Focus on the Synthesis and Reactions of Some New Pyridine Carbonitrile Derivatives as Antimicrobial and Antioxidant Agents
    Sayed, H. H.
    Flefel, E. M.
    Abd El-Fattah, A. M.
    El-Sofany, W. I.
    Hassan, A. M.
    EGYPTIAN JOURNAL OF CHEMISTRY, 2010, 53 (01): : 17 - 35
  • [45] 'Synthesis and Biological Assessment of Some New Acrylonitrile Derivatives as Potential Antitumor and Antimicrobial Agents'
    Taher, Azza Taher
    LIFE SCIENCE JOURNAL-ACTA ZHENGZHOU UNIVERSITY OVERSEAS EDITION, 2012, 9 (01): : 991 - 1005
  • [46] Design and synthesis of some azole derivatives as potential antimicrobial agents
    Deniz Sahin
    Hacer Bayrak
    Ahmet Demirbas
    Neslihan Demirbas
    Sengul Alpay-Karaoglu
    Medicinal Chemistry Research, 2012, 21 : 4485 - 4498
  • [47] SYNTHESIS OF NEW BENZIMIDAZOLE DERIVATIVES AS POTENTIAL ANTIMICROBIAL AGENTS
    BADAWEY, ESAM
    HASSAN, AMM
    KAPPE, T
    ARCHIV DER PHARMAZIE, 1991, 324 (06) : 355 - 357
  • [48] Synthesis of new benzotriazole derivatives: Antimicrobial and anticonvulsant agents
    Srivastava, SD
    Rawat, TR
    INDIAN JOURNAL OF CHEMISTRY SECTION B-ORGANIC CHEMISTRY INCLUDING MEDICINAL CHEMISTRY, 1999, 38 (05): : 623 - 627
  • [49] SYNTHESIS AND ANTIMICROBIAL ACTIVITY OF PHENYLSELENYL TRIBROMIDE AND ITS FUSED THIENOPYRIMIDINE DERIVATIVES
    Sharga, Boris M.
    Krivovjaz, Andrij O.
    Slivka, Mikhailo V.
    Lambruch, Larisa M.
    Cheypesh, Antonina V.
    Lendel, Vasil G.
    Nikolaychuk, Vitaly I.
    Markovich, Vladimir P.
    FARMACIA, 2016, 64 (04) : 512 - 520
  • [50] Design and synthesis of some azole derivatives as potential antimicrobial agents
    Sahin, Deniz
    Bayrak, Hacer
    Demirbas, Ahmet
    Demirbas, Neslihan
    Alpay-Karaoglu, Sengul
    MEDICINAL CHEMISTRY RESEARCH, 2012, 21 (12) : 4485 - 4498
12345