Clinical features and treatment outcome of children with acute lymphoblastic leukemia and hyperleukocytosis

被引：0

作者：

Rodriguez-Aguirre, Manuel, I ^{[1
]}

Hernandez-Cuellar, Esperanza ^{[1
]}

Espinoza-Roman, Victor H. ^{[1
]}

Acevedo-Segura, Virna G. ^{[1
]}

Lagos-Cordova, Elda Y. ^{[1
]}

Vera-Morales, Carlos D. ^{[1
]}

Vazquez-Garcia, Ruben E. ^{[1
]}

Palomo-Colli, Miguel A. ^{[1
,2
]}

机构：

[1] Hosp Reg Poza Rica, Dept Pediat, Poza Rica De Hidalgo, Ver, Mexico

[2] Hosp Infantil Mexico Dr Federico Gomez, Dept Oncol, Ciudad De Mexico, Mexico

来源：

GACETA MEXICANA DE ONCOLOGIA | 2021年 / 20卷

关键词：

Leukemias; Hypeleukocytosis; Medical treatment; Morbidity; Children; EARLY COMPLICATIONS; MANAGEMENT; LEUKAPHERESIS; LEUKOSTASIS;

D O I：

10.24875/j.gamo.21000031

中图分类号：

R73 [肿瘤学];

学科分类号：

100214 ;

摘要：

Introduction: Hyperleukocytosis in children with acute lymphoblastic leukemia (ALL) has been associated with early morbidity and mortality. Clinical Case: We analyzed clinical data from 6 patients with ALL. We documented adverse events within the first 28 days in patients with a white blood cell (WBC) count >= 100 x 10(9)/l and reviewed their management. The most frequent biochemical alterations were hyperuricemia and hyperglycemia There were no severe complications or deaths. Conclusions: With improved management, including supportive care, early mortality in patients with ALL and hyperleukocytosis could be decreased remarkably.

引用

页码：S23 / S27

页数：5

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