Asymmetric synthesis and fragmentation reactions of 2-alkyl- and 2,4-dialkyl-3-iodo-1-oxocyclohexan-2,4-carbolactones.: Single enantiomer preparation of Δα,β-butenolides, 2-alkyl-4-hydroxy-2-cyclohexen-1-ones and butyrolactones.

被引：17

作者：

Schultz, AG ^{[1
]}

Dai, MS ^{[1
]}

Khim, SK ^{[1
]}

Pettus, LP ^{[1
]}

Thakkar, K ^{[1
]}

机构：

[1] Rensselaer Polytech Inst, Dept Chem, Troy, NY 12180 USA

来源：

TETRAHEDRON LETTERS | 1998年 / 39卷 / 24期

基金：

美国国家卫生研究院;

关键词：

asymmetric synthesis; cycloadditions; enolates; fragmentation reactions;

D O I：

10.1016/S0040-4039(98)00785-0

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Fragmentation reactions of keto iodolactones 4 provide access to butenolides 5, 2-alkyl-4-hydroxy-2-cyclohexen-1-ones 6, and butyrolactones 9. Delta(alpha,beta)-Butenolides 5e and 5f were converted to heterocycles 14-16 by way of intramolecular cycloaddition reactions. (C) 1998 Elsevier Science Ltd. All rights reserved.

引用

页码：4203 / 4206

页数：4