Anti-inflammatory properties of bioactive titanium metals

被引：8
作者：
Yang, Bangcheng [1 ]
Gan, Lu [1 ]
Qu, Yang [1 ]
Yue, Chongxia [1 ]
机构：
[1] Sichuan Univ, Natl Engn Res Ctr Biomat, Chengdu 610064, Peoples R China
来源：
JOURNAL OF BIOMEDICAL MATERIALS RESEARCH PART A | 2010年 / 94A卷 / 03期
基金：
中国国家自然科学基金;
关键词：
anti-inflammatory; bioactivity; surface modification; titanium; SURFACES; INFECTION; BIOFILM; CALCIUM;
D O I：
10.1002/jbm.a.32743
中图分类号：
R318 [生物医学工程];
学科分类号：
0831 ;
摘要：
Anti-inflammatory properties of bioactive titanium metals prepared by anodic oxidation (AO-Ti) and alkali-heat (AH-Ti) treatments were studied by bacterial adhesion test and myeloperoxidase (MPO) activity assay methods. The bioactivities of the metals were also evaluated by apatite formation ability and osteoblasts culture experiments. Both metals could induce apatite formation and support osteoblasts proliferation. At the condition with normal incandescent light shine, both bioactive titanium metals had antibacterial adhesion properties compared with the titanium metal without treatment. The MPO activity assay proved that they both showed anti-inflammatory properties in vivo. The bioactive AO-Ti had better anti-inflammatory properties than the AH-Ti. It indicated that it is possible to optimize the anti-inflammatory properties of the bioactive titanium metals by different preparation methods. (C) 2010 Wiley Periodicals, Inc. J Biomed Mater Res Part A: 94A: 700-705, 2010
引用
收藏
页码：700 / 705
页数：6
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