Recent advances in organocatalytic asymmetric Michael reactions

被引：242
作者：
Zhang, Yong [1 ]
Wang, Wei [1 ]
机构：
[1] Lanzhou Univ, Coll Chem & Chem Engn, State Key Lab Appl Organ Chem, Lanzhou 730000, Gansu, Peoples R China
来源：
CATALYSIS SCIENCE & TECHNOLOGY | 2012年 / 2卷 / 01期
关键词：
ALPHA; BETA-UNSATURATED GAMMA-BUTYROLACTAM; DIVERSITY-ORIENTED SYNTHESIS; CONJUGATE ADDITION; 3-SUBSTITUTED BENZOFURAN-2(3H)-ONES; PROTECTED; 2-AMINO-1-NITROETHENES; ENANTIOSELECTIVE SYNTHESIS; MULTICOMPONENT SYNTHESIS; OXINDOLES BEARING; CASCADE REACTIONS; NITROALKENES;
D O I：
10.1039/c1cy00334h
中图分类号：
O64 [物理化学（理论化学）、化学物理学];
学科分类号：
070304 ; 081704 ;
摘要：
The Michael addition reaction represents one of the most powerful methods for the formation of carbon-carbon bonds in organic synthesis. Thanks to the rapid development of asymmetric organocatalysis, significant progress has been made during the past years in achieving organocatalytic asymmetric Michael reactions with a diverse combination of Michael donors and acceptors. Many new substrates have been accordingly applied in this reaction, together with the new approaches developed for the purpose of target- and diversity-oriented asymmetric synthesis. This review surveys the advances in target- and diversity-oriented asymmetric organocatalytic Michael reactions developed between 2009 and early 2011.
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页码：42 / 53
页数：12
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