Pneumocystis jirovecii Colonization in Preterm Newborns With Respiratory Distress Syndrome

被引：5
作者：
Szydlowicz, Magdalena [1 ]
Krolak-Olejnik, Barbara [2 ]
Vargas, Sergio L. [3 ]
Zajaczkowska, Zaneta [1 ]
Paluszynska, Dorota [2 ]
Szczygiel, Anna [2 ]
Matos, Olga [4 ]
Hendrich, Andrzej B. [1 ]
Kicia, Marta [1 ]
机构：
[1] Wroclaw Med Univ, Dept Biol & Med Parasitol, Ul J Mikulicza Radeckiego 9, PL-50345 Wroclaw, Poland
[2] Wroclaw Med Univ, Dept & Clin Neonatol, Wroclaw, Poland
[3] Univ Chile, Inst Ciencias Biomed, Fac Med, Santiago, Chile
[4] Univ Nova Lisboa, Inst Higiene & Med Trop, Unit Med Parasitol Global Hlth & Trop Med, Lisbon, Portugal
来源：
JOURNAL OF INFECTIOUS DISEASES | 2021年 / 225卷 / 10期
关键词：
Pneumocystis jirovecii; preterm infants; vertical transmission; respiratory distress syndrome; bronchopulmonary dysplasia;
D O I：
10.1093/infdis/jiab209
中图分类号：
R392 [医学免疫学]; Q939.91 [免疫学];
学科分类号：
100102 ;
摘要：
We describe the prevalence of Pneumocystis jirovecii in mother-infant pairs of very low birth weight newborns P. jirovecii in patients' specimens. Pneumocystis DNA was detected in 8 nasopharyngeal aspirates (14%) of 56 newborns and in 7 oral washes (21%) of 34 mothers. Pneumocystis detection immediately after birth suggests the possibility of its transplacental transmission. Compared to noncolonized infants, more frequent occurrence of bronchopulmonary dysplasia was seen in colonized infants (P = .02), suggesting a potential clinical importance of this pathogen in abnormal lung development.
引用
收藏
页码：1807 / 1810
页数：4
相关论文
共 13 条
  • [1] P. carinii induces selective alterations in component expression and biophysical activity of lung surfactant
    Atochina, EN
    Beers, MF
    Scanlon, ST
    Preston, AM
    Beck, JM
    [J]. AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY, 2000, 278 (03) : L599 - L609
  • [2] Pneumocystis jirovecii colonisation in pregnant women and newborns in Lima, Peru
    Garcia, Coralith
    Ochoa, Theresa
    Neyra, Edgar
    Bustamante, Beatriz
    Ponce, Carolina
    Calderon, Enrique J.
    Vargas, Sergio L.
    [J]. REVISTA IBEROAMERICANA DE MICOLOGIA, 2020, 37 (01): : 24 - 27
  • [3] Use of Oropharyngeal Washes to Diagnose and Genotype Pneumocystis jirovecii
    Juliano, Jonathan J.
    Barnett, Eric
    Parobek, Christian M.
    Taylor, Steve M.
    Meshnick, Steven R.
    Stone, Stephen
    Chang, Emily
    Fong, Serena
    Huang, Laurence
    [J]. OPEN FORUM INFECTIOUS DISEASES, 2015, 2 (03):
  • [4] GENETIC-VARIATION AMONG PNEUMOCYSTIS-CARINII HOMINIS ISOLATES IN RECURRENT PNEUMOCYSTOSIS
    KEELY, SP
    STRINGER, JR
    BAUGHMAN, RP
    LINKE, MJ
    WALZER, PD
    SMULIAN, AG
    [J]. JOURNAL OF INFECTIOUS DISEASES, 1995, 172 (02) : 595 - 598
  • [5] Effect of oral washes on the diagnosis of Pneumocystis carinii pneumonia with a low parasite burden and on detection of organisms in subclinical infections
    Matos, O
    Costa, MC
    Lundgren, B
    Caldeira, L
    Aguiar, P
    Antunes, F
    [J]. EUROPEAN JOURNAL OF CLINICAL MICROBIOLOGY & INFECTIOUS DISEASES, 2001, 20 (08) : 573 - 575
  • [6] Mogensen UB, 2012, J STAT SOFTW, V50, P1
  • [7] Vertical Transmission of Pneumocystis jirovecii in Humans
    Montes-Cano, Marco A.
    Chabe, Magali
    Fontillon-Alberdi, Maria
    de la Horra, Carmen
    Respaldiza, Nieves
    Medrano, Francisco J.
    Varela, Jose M.
    Dei-Cas, Eduardo
    Calderon, Enrique J.
    [J]. EMERGING INFECTIOUS DISEASES, 2009, 15 (01) : 125 - 127
  • [8] Early Acquisition of Pneumocystis jirovecii Colonization and Potential Association With Respiratory Distress Syndrome in Preterm Newborn Infants
    Rojas, Pilar
    Friaza, Vicente
    Garcia, Elisa
    de la Horra, Carmen
    Vargas, Sergio L.
    Calderon, Enrique J.
    Pavon, Antonio
    [J]. CLINICAL INFECTIOUS DISEASES, 2017, 65 (06) : 976 - 981
  • [9] European Consensus Guidelines on the Management of Respiratory Distress Syndrome-2019 Update
    Sweet, David G.
    Carnielli, Virgilio
    Greisen, Gorm
    Hallman, Mikko
    Ozek, Eren
    te Pas, Arjan
    Plavka, Richard
    Roehr, Charles C.
    Saugstad, Ola D.
    Simeoni, Umberto
    Speer, Christian P.
    Vento, Maximo
    Visser, Gerhard H. A.
    Halliday, Henry L.
    [J]. NEONATOLOGY, 2019, 115 (04) : 432 - 450
  • [10] Near-Universal Prevalence of Pneumocystis and Associated Increase in Mucus in the Lungs of Infants With Sudden Unexpected Death
    Vargas, Sergio L.
    Ponce, Carolina A.
    Gallo, Miriam
    Perez, Francisco
    Astorga, J. -Felipe
    Bustamante, Rebeca
    Chabe, Magali
    Durand-Joly, Isabelle
    Iturra, Pablo
    Miller, Robert F.
    Aliouat, El Moukthar
    Dei-Cas, Eduardo
    [J]. CLINICAL INFECTIOUS DISEASES, 2013, 56 (02) : 171 - 179
12