Use of Cardiac Contractility Modulation as Bridge to Transplant in an Obese Patient With Advanced Heart Failure: A Case Report

被引：4

作者：

Masarone, Daniele ^{[1
]}

Petraio, Andrea ^{[2
]}

Fiorentino, Antonio ^{[3
]}

Dellegrottaglie, Santo ^{[4
,5
]}

Valente, Fabio ^{[1
]}

Ammendola, Ernesto ^{[1
]}

Nigro, Gerardo ^{[6
]}

Pacileo, Giuseppe ^{[1
]}

机构：

[1] Monaldi Hosp, AORN Colli, Dept Cardiol, Heart Failure Unit, Naples, Italy

[2] Monaldi Hosp, AORN Colli, Dept Cardiac Surg & Transplants, Heart Transplant Unit, Naples, Italy

[3] Impulse Dynam Germany, Frankfurt, Germany

[4] Osped Accreditato Villa Fiori, Div Cardiol, Naples, Italy

[5] Icahn Sch Med Mt Sinai, Marie Josee & Henry R Kravis Ctr Cardiovasc Hlth, Zena & Michael A Wiener Cardiovasc Inst, New York, NY 10029 USA

[6] Univ Campania Luigi Vanvitelli, Monaldi Hosp, Dept Med Translat Sci, Naples, Italy

来源：

FRONTIERS IN CARDIOVASCULAR MEDICINE | 2022年 / 9卷

关键词：

heart failure reduced ejection fraction; advanced heart failure; cardiac contractility modulation; obesity; dilated cardiomyopathy; SURVIVAL; OUTCOMES; LEVOSIMENDAN; EPIDEMIOLOGY; OUTPATIENTS; EFFICACY; CURRENTS;

D O I：

10.3389/fcvm.2022.833143

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

Cardiac contractility modulation (CCM) is a novel device-based therapy in patients with heart failure with reduced ejection fraction (HFrEF). In randomized clinical trials and real-life studies, CCM has been shown to improve exercise tolerance and quality of life, reverse left ventricular remodeling and reduce hospitalization in patients with HFrEF. In this case report, we describe for the first time the use of CCM as a "bridge to transplant" in a young obese patient with advanced heart failure due to non-ischemic dilated cardiomyopathy. The patient had a poor quality of life and frequent heart failure-related hospitalizations despite the optimal medical therapy and, due to obesity, a suitable heart donor was unlikely to be identified in the short term and due to severe obesity risk of complications after implantation of a left ventricular assist device (LVAD) was very high.

引用

页数：5

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