Steroidal triglycosides, kurilensosides A, B, and C, and other polar steroids from the Far Eastern starfish Hippasteria kurilensis

被引：16

作者：

Kicha, Alla A. ^{[1
]}

Ivanchina, Natalia V. ^{[1
]}

Kalinovsky, Anatoly I. ^{[1
]}

Dmitrenok, Pavel S. ^{[1
]}

Agafonova, Irina G. ^{[1
]}

Stonik, Valentin A. ^{[1
]}

机构：

[1] Russian Acad Sci, Far E Branch, Pacific Inst Bioorgan Chem, Vladivostok 690022, Russia

来源：

JOURNAL OF NATURAL PRODUCTS | 2008年 / 71卷 / 05期

关键词：

D O I：

10.1021/np070637x

中图分类号：

Q94 [植物学];

学科分类号：

071001 ;

摘要：

Three novel steroidal triglycosides, designated as kurilensosides A, B, and C (1-3), were isolated along with a new steroidal diglycoside, kurilensoside D (4), and two new (6, 7) and one known (5) polyhydroxysteroid from the alcoholic extract of the Far Eastern starfish Hippasteria kurilensis. Compounds 1-3 are the first triglycosides containing two carbohydrate chains found from starfish. The structures of 1-7 were elucidated by spectroscopic methods (mainly 2D NMR) and chemical derivatization. Glycosides 1-4 and steroids 6 and 7 inhibited sea urchin egg fertilization by sperm preincubated with these compounds.

引用

页码：793 / 798

页数：6

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