Reduction of catheter-related bloodstream infections through the use of a central venous line bundle: Epidemiologic and economic consequences

被引:77
作者
Kim, James S. [1 ]
Holtom, Paul [1 ,2 ]
Vigen, Cheryl [3 ]
机构
[1] USC & LAC Med Ctr, USC Dept Infect Dis, Los Angeles, CA USA
[2] USC & LAC Med Ctr, USC Dept Infect Control, Los Angeles, CA USA
[3] Univ So Calif, Keck Sch Med, Dept Biostat, Los Angeles, CA 90033 USA
关键词
Catheter-related bloodstream infections; CRBSI; bundle; cost control; CRITICALLY-ILL PATIENTS; CARE; PREVENTION; GUIDELINES;
D O I
10.1016/j.ajic.2010.11.005
中图分类号
R1 [预防医学、卫生学];
学科分类号
1004 ; 120402 ;
摘要
Background: Central venous lines (CVLs) are used extensively in intensive care units (ICUs) but can sometimes lead to catheter-related blood stream infections (CRBSIs). This study evaluated a "CVL bundle" to see whether the CRBSI rate would decrease, analyze any changes in the flora of CRBSIs, and project any decrease in health care costs. Methods: The CVL bundle was implemented on all patients admitted to the ICU starting January 2008. Data from CRBSI rates from 2006 and 2007 were pooled to compare the intervention. A Poisson analysis generated a relative risk reduction. Determination of costs were made by taking the excess length of stay multiplied by other costs (supplies, medications, cost of replacement of CVL) at our institution. Results: Overall infection rates decreased with an improvement in CRBSIs in all ICUs that participated. Although the proportion of gram-negative organisms did not change significantly, there was a decrease in the proportion of gram-positive infections (P = .05) and an increase in fungal infections (P = .04). The total excess cost per organism was determined by the following: total excess cost = excess length of stay + replacement of CVL + drug administration + antibiotic cost. The weighted excess cost took the total excess cost times a correction factor based on organism frequency. The total excess cost of any given CRBSI is approximately $32,254. Conclusion: Preventing CRBSIs can improve patient care while reducing hospital stays, costs, and possible mortality. CVL bundles are fairly easy to perform with reproducible results.
引用
收藏
页码:640 / 646
页数:7
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