Postpartum corticosteroids in HELLP syndrome - standard to prompt recovery

被引:7
作者
Gabor, M. [1 ]
Drab, M. [1 ]
Holoman, K. [1 ]
机构
[1] Comenius Univ, Univ Hosp Bratislava, Dept Obstet & Gynaecol 2, Bratislava, Slovakia
来源
BRATISLAVA MEDICAL JOURNAL-BRATISLAVSKE LEKARSKE LISTY | 2016年 / 117卷 / 07期
关键词
HELLP syndrome; corticosteroids; complications; postpartum; recovery; ELEVATED LIVER-ENZYMES; PLATELET COUNT SYNDROME; SEVERE PREECLAMPSIA; CLINICAL SYMPTOMS; MATERNAL BENEFIT; HEMOLYSIS; MANAGEMENT; DIAGNOSIS; PREGNANCY; THERAPY;
D O I
10.4149/BLL_2016_082
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
OBJECTIVES: To perform a complex review of HELLP syndrome and its treatment from up to date scientific literature. Study of the interresting treatement regime of the patient. METHODS: Complex analysis of the syndrome, systematic search of medical scientific databases and Slovak Medical Library. Analysis of the life threatening state of the patient, retrospective analysis of the diagnostics, treatment, acute management, complications and clinical results. RESULTS: According to up to date literature and our good clinical experiences we can encourage the use of high-dose corticosteroid therapy in HELLP syndrome. CONCLUSION: The most recent studies definitely recommend the high dose corticosteroid treatment in recovery management by the HELLP syndrome. We have used the high-dose corticosteroid regime as a recovery management for the patient with postpartum HELLP with very good clinical and laboratory response followed by prompt recovery of the patient and without other complications. We want to support and empasize the indication of the Dexamethasone regiment by HELLP, becouse the clinical experiences with this treatment are not well-known and usually the corticosteroids are not given to the patients with HELLP, or the treatment is "daemonized". Our clinical experience with this treatment was successful and the patient definitely profited of it. We support the opinion, that the benefit of described regiment highly exceedes the possible adverse effects of the therapy (Fig. 8, Ref. 61). Text in PDF www.elis.sk.
引用
收藏
页码:418 / 424
页数:7
相关论文
共 59 条
[1]   Liver Failure in Pregnancy [J].
Bacak, Stephen J. ;
Thornburg, Loralei L. .
CRITICAL CARE CLINICS, 2016, 32 (01) :61-+
[2]   Diagnosis and management of hemolysis, elevated liver enzymes, and low platelets syndrome [J].
Barton, JR ;
Sibai, BM .
CLINICS IN PERINATOLOGY, 2004, 31 (04) :807-+
[3]   Choice of glucocorticoid in HELLP syndrome - dexamethasone versus betamethasone: revisiting the dilemma [J].
Basaran, Ahmet ;
Basaran, Mustafa ;
Sen, Cihat .
JOURNAL OF MATERNAL-FETAL & NEONATAL MEDICINE, 2012, 25 (12) :2597-2600
[4]   HELLP syndrome: The state of the art [J].
Baxter, JSK ;
Weinstein, L .
OBSTETRICAL & GYNECOLOGICAL SURVEY, 2004, 59 (12) :838-845
[5]  
Bayraktaroglu Ziya, 2006, Turk J Gastroenterol, V17, P99
[6]   The Differential Diagnosis of Thrombocytopenia in Pregnancy An interdisciplinary challenge [J].
Bergmann, Frauke ;
Rath, Werner .
DEUTSCHES ARZTEBLATT INTERNATIONAL, 2015, 112 (47) :795-+
[7]   Are clinical symptoms more predictive than laboratory parameters for adverse maternal outcome in HELLP syndrome? [J].
Cavkaytar, Sabri ;
Ugurlu, Evin Nil ;
Karaer, Abdullah ;
Tapisiz, Omer Lutfi ;
Danisman, Nuri .
ACTA OBSTETRICIA ET GYNECOLOGICA SCANDINAVICA, 2007, 86 (06) :648-651
[8]   Extensive hepatic infarction in severe preeclampsia as part of the HELLP syndrome (hemolysis, elevated liver enzymes, and low platelets): Evolution of CT findings and successful treatment with plasma exchange therapy [J].
Chou, Min-Min ;
Chen, Ya-Fang ;
Kung, Hsiao-Fan ;
Liu, Chih-Ku ;
Sun, Lou ;
Chen, Wei-Chi ;
Tseng, Jeng-Jhy ;
Lee, Bor-Jen .
TAIWANESE JOURNAL OF OBSTETRICS & GYNECOLOGY, 2012, 51 (03) :418-420
[9]   Outcomes at 2 years of age after repeat doses of antenatal corticosteroids [J].
Crowther, Caroline A. ;
Doyle, Lex W. ;
Haslam, Ross R. ;
Hiller, Janet E. ;
Harding, Jane E. ;
Robinson, Jeffrey S. .
NEW ENGLAND JOURNAL OF MEDICINE, 2007, 357 (12) :1179-1189
[10]   Anesthetic considerations in HELLP syndrome [J].
del-Rio-Vellosillo, M. ;
Garcia-Medina, J. J. .
ACTA ANAESTHESIOLOGICA SCANDINAVICA, 2016, 60 (02) :144-157