Prevalence and Risk Factors of Excessive Daytime Sleepiness in a Community Sample of Young Children: The Role of Obesity, Asthma, Anxiety/Depression, and Sleep

被引:105
作者
Calhoun, Susan L. [1 ]
Vgontzas, Alexandros N.
Fernandez-Mendoza, Julio
Mayes, Susan D.
Tsaoussoglou, Marina
Basta, Maria
Bixler, Edward O.
机构
[1] Penn State Univ, Milton S Hershey Med Ctr, Coll Med, Dept Psychiat H073,Sleep Res & Treatment Ctr, Hershey, PA 17033 USA
关键词
Children; excessive daytime sleepiness; obesity; anxiety/depression; POPULATION-SAMPLE; DEPRESSION; APNEA; BEHAVIOR; ANXIETY; ADHD;
D O I
10.1093/sleep/34.4.503
中图分类号
R74 [神经病学与精神病学];
学科分类号
摘要
Study Objectives: We investigated the prevalence and association of excessive daytime sleepiness (EDS) with a wide range of factors (e. g., medical complaints, obesity, objective sleep [including sleep disordered breathing], and parent-reported anxiety/depression and sleep difficulties) in a large general population sample of children. Few studies have researched the prevalence and predictors of EDS in young children, none in a general population sample of children, and the results are inconsistent. Design: Cross-sectional Setting: Population -based. Participants: 508 school-aged children from the general population. Interventions: N/A Measurements and Results: Children underwent a 9-hour polysomnogram (PSG), physical exam, and parent completed health, sleep and psychological questionnaires. Children were divided into 2 groups: those with and without parent reported EDS. The prevalence of subjective EDS was approximately 15%. Significant univariate relationships were found between children with EDS and BMI percentile, waist circumference, heartburn, asthma, and parent reported anxiety/depression, and sleep difficulties. The strongest predictors of EDS were waist circumference, asthma, and parent-reported symptoms of anxiety/depression and trouble falling asleep. All PSG sleep variables including apnea/hypopnea index, caffeine consumption, and allergies were not significantly related to EDS. Conclusions: It appears that the presence of EDS is more strongly associated with obesity, asthma, parent reported anxiety/depression, and trouble falling asleep than with sleep disordered breathing (SDB) or objective sleep disruption per se. Our findings suggest that children with EDS should be thoroughly assessed for anxiety/depression, nocturnal sleep difficulties, asthma, obesity, and other metabolic factors, whereas objective sleep findings may not be as clinically useful.
引用
收藏
页码:503 / 507
页数:5
相关论文
共 24 条
[1]   Advances in empirically based assessment:: Revised cross-informant syndromes and new DSM-oriented scales for the CBCL, YSR, and TRF:: Comment on Lengua, Sadowksi, Friedrich, and Fisher (2001) [J].
Achenbach, TM ;
Dumenci, L .
JOURNAL OF CONSULTING AND CLINICAL PSYCHOLOGY, 2001, 69 (04) :699-702
[2]  
Ali NJ, 1996, EUR J PEDIATR, V155, P56, DOI 10.1007/BF02309859
[3]  
[Anonymous], 2000, DIAGN STAT MAN MENT, DOI DOI 10.1176/APPI.BOOKS.9780890425787
[4]  
[Anonymous], 2005, INT CLASSIFICATION S
[5]  
Basta M, 2008, J CLIN SLEEP MED, V4, P19
[6]   Blood Pressure Associated With Sleep-Disordered Breathing in a Population Sample of Children [J].
Bixler, Edward O. ;
Vgontzas, Alexandros N. ;
Lin, Hung-Mo ;
Liao, Duanping ;
Calhoun, Susan ;
Fedok, Fred ;
Vlasic, Vukmir ;
Graff, Gavin .
HYPERTENSION, 2008, 52 (05) :841-846
[7]   Excessive daytime sleepiness in a general population sample: The role of sleep apnea, age, obesity, diabetes, and depression [J].
Bixler, EO ;
Vgontzas, AN ;
Lin, HM ;
Calhoun, SL ;
Vela-Bueno, AV ;
Kales, A .
JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM, 2005, 90 (08) :4510-4515
[8]   Sleep and behavioral/emotional problems in children: A population-based study [J].
Bos, S. Carvalho ;
Gomes, A. ;
Clemente, V. ;
Marques, M. ;
Pereira, A. T. ;
Maia, B. ;
Soares, M. J. ;
Cabral, A. S. ;
Macedo, A. ;
Gozal, D. ;
Azevedo, M. H. .
SLEEP MEDICINE, 2009, 10 (01) :66-74
[9]   Sleep-disordered breathing, behavior, and cognition in children before and after adenotonsillectomy [J].
Chervin, RD ;
Ruzicka, DL ;
Giordani, BJ ;
Weatherly, RA ;
Dillon, JE ;
Hodges, EK ;
Marcus, CL ;
Guire, KE .
PEDIATRICS, 2006, 117 (04) :E769-E778
[10]   Sleep disturbance and daytime symptoms in wheezing school-aged children [J].
Desager, KN ;
Nelen, V ;
Weyler, JJJ ;
De Backer, WA .
JOURNAL OF SLEEP RESEARCH, 2005, 14 (01) :77-82