Statins:: new therapeutic possibilities for osteoporosis?

被引:1
作者
Laufs, U [1 ]
Werner, N [1 ]
Böhm, M [1 ]
Nickenig, G [1 ]
机构
[1] Univ Saarlandes Kliniken, Med Klin & Poliklin, D-66421 Homburg, Germany
关键词
D O I
10.1055/s-2001-13809
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
引用
收藏
页码:565 / 568
页数:4
相关论文
共 24 条
[11]   REGULATION OF THE MEVALONATE PATHWAY [J].
GOLDSTEIN, JL ;
BROWN, MS .
NATURE, 1990, 343 (6257) :425-430
[12]   The intracellular target for the antiresorptive aminobisphosphonate drugs in Dictyostelium discoideum is the enzyme farnesyl diphosphate synthase [J].
Grove, JE ;
Brown, RJ ;
Watts, DJ .
JOURNAL OF BONE AND MINERAL RESEARCH, 2000, 15 (05) :971-981
[13]   Targeting Rho in cardiovascular disease [J].
Laufs, U ;
Liao, JK .
CIRCULATION RESEARCH, 2000, 87 (07) :526-528
[14]   New findings on the action of 3-hydroxy-3-methylglutaryl coenzyme A reductase (HMG-CoA-reductase) inhibitors [J].
Laufs, U ;
Bohm, M ;
Liao, JK .
DEUTSCHE MEDIZINISCHE WOCHENSCHRIFT, 1997, 122 (41) :1255-1259
[15]   Postmenopausal osteoporosis - Strategies for preventing bone loss, avoiding fracture [J].
McGarry, KA ;
Kiel, DP .
POSTGRADUATE MEDICINE, 2000, 108 (03) :79-+
[16]   HMG-CoA reductase inhibitors and the risk of fractures [J].
Meier, CR ;
Schlienger, RG ;
Kraenzlin, ME ;
Schlegel, B ;
Jick, H .
JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION, 2000, 283 (24) :3205-3210
[17]   Stimulation of bone formation in vitro and in rodents by statins [J].
Mundy, G ;
Garrett, R ;
Harris, S ;
Chan, J ;
Chen, D ;
Rossini, G ;
Boyce, B ;
Zhao, M ;
Gutierrez, G .
SCIENCE, 1999, 286 (5446) :1946-1949
[18]   Alendronate for the treatment of osteoporosis in men [J].
Orwoll, E ;
Ettinger, M ;
Weiss, S ;
Miller, P ;
Kendler, D ;
Graham, J ;
Adami, S ;
Weber, K ;
Lorenc, R ;
Pietschmann, P ;
Vandormael, K ;
Lombardi, A ;
Adachi, JD ;
Bell, N ;
Body, JJ ;
Castro, A ;
Daifotis, A ;
Felsenberg, D ;
Gilchrist, N ;
Hoffman, A ;
Maricic, M ;
Rizzoli, R ;
Silverman, S ;
Valeriano, J .
NEW ENGLAND JOURNAL OF MEDICINE, 2000, 343 (09) :604-610
[19]   Pathophysiology and treatment of osteoporosis [J].
Pietschmann, P ;
Peterlik, M .
RADIOLOGE, 1999, 39 (03) :228-234
[20]  
RAUE F, 2000, BISPHOSPHONATE INTER, V40, P448