Simultaneous assessment of pulsating and total blood in inflammatory skin lesions using functional diffuse reflectance spectroscopy in the visible range

被引：9

作者：

Seo, InSeok ^{[1
]}

Bargo, Paulo R. ^{[1
]}

Kollias, Nikiforos ^{[1
]}

机构：

[1] Johnson & Johnson Consumer Prod Co, Skillman, NJ 08558 USA

来源：

JOURNAL OF BIOMEDICAL OPTICS | 2010年 / 15卷 / 06期

关键词：

skin lesion; blood flow; diffuse reflectance spectra; heart pulsation;

D O I：

10.1117/1.3524191

中图分类号：

Q5 [生物化学];

学科分类号：

071010 ; 081704 ;

摘要：

We present a simple and cost-effective optical technique for the simultaneous assessment of pulsating and total blood noninvasively in an inflammatory skin lesion. Acquisitions of diffuse reflectance spectra in the visible range at 6 Hz are used to trace the oscillating components of reflectance. Measurements on erythematous lesions from a UV insult show slow changing signal at about 0.1 Hz and heart-driven regular oscillations at about 1 Hz simultaneously. The results demonstrate the potential of the technique in monitoring both pulsating and steady components of the blood in inflammatory lesions of the skin. (C) 2010 Society of Photo-Optical Instrumentation Engineers. [DOI: 10.1117/1.3524191]

引用

页数：3

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