Polyglutamine aggregation impairs nuclear export of huntingtin.

被引：0
|
作者：
Cornett, JC [1 ]
Li, SH [1 ]
Li, XJ [1 ]
机构：
[1] Emory Univ, Dept Human Genet, Atlanta, GA 30322 USA
来源：
AMERICAN JOURNAL OF HUMAN GENETICS | 2003年 / 73卷 / 05期
关键词：
D O I：
暂无
中图分类号：
Q3 [遗传学];
学科分类号：
071007 ; 090102 ;
摘要：
2450
引用
收藏
页码：586 / 586
页数：1
相关论文
共 50 条
  • [41] Huntingtin toxicity in yeast model depends on polyglutamine aggregation mediated by a prion-like protein Rnq1
    Meriin, AB
    Zhang, XQ
    He, XW
    Newnam, GP
    Chernoff, YO
    Sherman, MY
    JOURNAL OF CELL BIOLOGY, 2002, 157 (06): : 997 - 1004
  • [42] Membrane Interactions Accelerate the Self-Aggregation of Huntingtin Exon 1 Fragments in a Polyglutamine Length-Dependent Manner
    Marquette, Arnaud
    Aisenbrey, Christopher
    Bechinger, Burkhard
    INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, 2021, 22 (13)
  • [43] HNRNP Q suppresses polyglutamine huntingtin aggregation by post-transcriptional regulation of vaccinia-related kinase 2
    Ryu, Hye Guk
    Kim, Sangjune
    Lee, Saebom
    Lee, Eunju
    Kim, Hyo-Jin
    Kim, Do-Yeon
    Kim, Kyong-Tai
    JOURNAL OF NEUROCHEMISTRY, 2019, 149 (03) : 413 - 426
  • [44] THE ROLE OF ERN1, A REGULATOR IN ER STRESS-MEDIATED AGGREGATION OF POLYGLUTAMINE-EXTENDED MUTANT HUNTINGTIN
    Lee, H.
    Noh, J. Y.
    Jung, Y. K.
    JOURNAL OF NEUROCHEMISTRY, 2009, 110 : 193 - 193
  • [45] An investigation into the role of turn-supporting motif in polyglutamine binding peptide (QBP1) in Huntingtin aggregation inhibition
    Belwal, V. K.
    Datta, D.
    Chaudhary, N.
    FEBS OPEN BIO, 2021, 11 : 176 - 176
  • [46] Reversal of a full-length mutant huntingtin neuronal cell phenotype by chemical inhibitors of polyglutamine-mediated aggregation
    Wang, J
    Gines, S
    MacDonald, ME
    Gusella, JF
    BMC NEUROSCIENCE, 2005, 6 (1)
  • [47] MOLECULAR PATHWAYS TO POLYGLUTAMINE AGGREGATION
    Robertson, Amy L.
    Bottomley, Stephen P.
    TANDEM REPEAT POLYMORPHISMS: GENETIC PLASTICITY, NEURAL DIVERSITY AND DISEASE, 2012, 769 : 115 - 124
  • [48] Impaired Nuclear Export of Polyglutamine-Expanded Androgen Receptor in Spinal and Bulbar Muscular Atrophy
    Frederick J. Arnold
    Anna Pluciennik
    Diane E. Merry
    Scientific Reports, 9
  • [49] Impaired Nuclear Export of Polyglutamine-Expanded Androgen Receptor in Spinal and Bulbar Muscular Atrophy
    Arnold, Frederick J.
    Pluciennik, Anna
    Merry, Diane E.
    SCIENTIFIC REPORTS, 2019, 9 (1)
  • [50] Studying of aggregation of nuclear export protein (NEP) Influenza virus A
    Golovko, A. O.
    Koroleva, O. N.
    Dubrovin, E. V.
    Radyukhin, V. A.
    Drutsa, V. L.
    FEBS JOURNAL, 2017, 284 : 34 - 35
12345