Polyglutamine aggregation impairs nuclear export of huntingtin.

被引：0
|
作者：
Cornett, JC [1 ]
Li, SH [1 ]
Li, XJ [1 ]
机构：
[1] Emory Univ, Dept Human Genet, Atlanta, GA 30322 USA
来源：
AMERICAN JOURNAL OF HUMAN GENETICS | 2003年 / 73卷 / 05期
关键词：
D O I：
暂无
中图分类号：
Q3 [遗传学];
学科分类号：
071007 ; 090102 ;
摘要：
2450
引用
收藏
页码：586 / 586
页数：1
相关论文
共 50 条
  • [31] Aggregation in polyglutamine disease: Recruitment of resident nuclear proteins to polyglutamine inclusions depends upon disease protein context
    Chai, YH
    Paulson, HL
    NEUROLOGY, 2001, 56 (08) : A130 - A130
  • [32] Polyglutamine-Expanded Huntingtin Exacerbates Age-Related Disruption of Nuclear Integrity and Nucleocytoplasmic Transport
    Gasset-Rosa, Fatima
    Chillon-Marinas, Carlos
    Goginashvili, Alexander
    Atwal, Ranjit Singh
    Artates, Jonathan W.
    Tabet, Ricardos
    Wheeler, Vanessa C.
    Bang, Anne G.
    Cleveland, Don W.
    Lagier-Tourenne, Clotilde
    NEURON, 2017, 94 (01) : 48 - +
  • [33] Thermodynamics of Huntingtin Aggregation
    Tam T M Phan
    Schmit, Jeremy D.
    BIOPHYSICAL JOURNAL, 2020, 118 (12) : 2989 - 2996
  • [34] Polyglutamine repeat length-dependent proteolysis of huntingtin
    Sun, B
    Fan, W
    Balciunas, A
    Cooper, JK
    Bitan, G
    Steavenson, S
    Denis, PE
    Young, Y
    Adler, B
    Daugherty, L
    Manoukian, R
    Elliott, G
    Shen, WY
    Talvenheimo, J
    Teplow, DB
    Haniu, M
    Haldankar, R
    Wypych, J
    Ross, CA
    Citron, M
    Richards, WG
    NEUROBIOLOGY OF DISEASE, 2002, 11 (01) : 111 - 122
  • [35] Polyglutamine expansion in huntingtin alters its interaction with phospholipids
    Kegel, Kimberly B.
    Sapp, Ellen
    Alexander, Jonathan
    Valencia, Antonio
    Reeves, Patrick
    Li, Xueyi
    Masso, Nicholas
    Sobin, Lindsay
    Aronin, Neil
    DiFiglia, Marian
    JOURNAL OF NEUROCHEMISTRY, 2009, 110 (05) : 1585 - 1597
  • [36] Huntingtin Aggregation Impairs Autophagy, Leading to Argonaute-2 Accumulation and Global MicroRNA Dysregulation
    Pircs, Karolina
    Petri, Rebecca
    Madsen, Sofia
    Brattas, Per Ludvik
    Vuono, Romina
    Ottosson, Daniella R.
    St-Amour, Isabelle
    Hersbach, Bob A.
    Matusiak-Bruckner, Monika
    Lundh, Sofia Hult
    Petersen, Asa
    Deglon, Nicole
    Hebert, Sebastien S.
    Parmar, Malin
    Barker, Roger A.
    Jakobsson, Johan
    CELL REPORTS, 2018, 24 (06): : 1397 - 1406
  • [37] Huntingtin polyglutamine expansions cause pleiotropic transport defects
    Hendricks, Adam G.
    Prowse, Emily N. P.
    Turkalj, Brooke
    Pouladi, Mahmoud A.
    BIOPHYSICAL JOURNAL, 2024, 123 (03) : 189A - 189A
  • [38] A structure-based analysis of huntingtin mutant polyglutamine aggregation and toxicity: evidence for a compact beta-sheet structure
    Poirier, MA
    Jiang, H
    Ross, CA
    HUMAN MOLECULAR GENETICS, 2005, 14 (06) : 765 - 774
  • [39] Reversal of a full-length mutant huntingtin neuronal cell phenotype by chemical inhibitors of polyglutamine-mediated aggregation
    Jin Wang
    Silvia Gines
    Marcy E MacDonald
    James F Gusella
    BMC Neuroscience, 6
  • [40] Solid-state nuclear magnetic resonance in the structural study of polyglutamine aggregation
    van der Wel, Patrick C. A.
    BIOCHEMICAL SOCIETY TRANSACTIONS, 2024, 52 (02) : 719 - 731
12345