Polyglutamine aggregation impairs nuclear export of huntingtin.

被引：0
|
作者：
Cornett, JC [1 ]
Li, SH [1 ]
Li, XJ [1 ]
机构：
[1] Emory Univ, Dept Human Genet, Atlanta, GA 30322 USA
来源：
AMERICAN JOURNAL OF HUMAN GENETICS | 2003年 / 73卷 / 05期
关键词：
D O I：
暂无
中图分类号：
Q3 [遗传学];
学科分类号：
071007 ; 090102 ;
摘要：
2450
引用
收藏
页码：586 / 586
页数：1
相关论文
共 50 条
  • [1] Polyglutamine expansion of huntingtin impairs its nuclear export
    Jonathan Cornett
    Fengli Cao
    Chuan-En Wang
    Christopher A Ross
    Gillian P Bates
    Shi-Hua Li
    Xiao-Jiang Li
    Nature Genetics, 2005, 37 : 198 - 204
  • [2] Polyglutamine expansion of huntingtin impairs its nuclear export
    Cornett, J
    Cao, FK
    Wang, CE
    Ross, CA
    Bates, GP
    Li, SH
    Li, XJ
    NATURE GENETICS, 2005, 37 (02) : 198 - 204
  • [3] Transcriptional regulation by huntingtin.
    Jones, L
    Duce, J
    Hartog, C
    Elliston, L
    Caswell, R
    Wilkinson, F
    Morris, GE
    Man, NT
    Neal, J
    Harper, PS
    AMERICAN JOURNAL OF HUMAN GENETICS, 2000, 67 (04) : 365 - 365
  • [4] Polyglutamine core is the primary driver of seeded huntingtin aggregation
    Skeens, Adam
    Legleiter, Justin A.
    BIOPHYSICAL JOURNAL, 2023, 122 (03) : 353A - 354A
  • [5] The polyglutamine domain is the primary driver of seeding in huntingtin aggregation
    Skeens, Adam
    Siriwardhana, Chathuranga
    Massinople, Sophia E.
    Wunder, Michelle M.
    Ellis, Zachary L.
    Keith, Kaitlyn M.
    Girman, Tyler
    Frey, Shelli L.
    Legleiter, Justin
    PLOS ONE, 2024, 19 (03):
  • [6] Endogenous huntingtin modulates the cellular toxicity of mutant huntingtin.
    Leavitt, BR
    Hackam, A
    Gutekunst, CA
    McCutcheon, K
    Yassa, A
    Singaraja, R
    Kimel, G
    Hersch, S
    Vogl, W
    Hayden, MR
    AMERICAN JOURNAL OF HUMAN GENETICS, 1999, 65 (04) : A457 - A457
  • [7] Huntingtin Polyglutamine-Dependent Protein Aggregation in Reconstituted Cells
    Machida, Kodai
    Kanzawa, Kuru
    Shigeta, Tomoaki
    Yamamoto, Yuki
    Tsumoto, Kanta
    Imataka, Hiroaki
    ACS SYNTHETIC BIOLOGY, 2018, 7 (02): : 377 - 383
  • [8] Dynamic of inclusion formation and processing of huntingtin.
    Trottier, Y
    Lunkes, A
    Lindenberg, KS
    Devys, D
    Landwehrmeyer, GB
    Mandel, JL
    AMERICAN JOURNAL OF HUMAN GENETICS, 2001, 69 (04) : 616 - 616
  • [9] Chaperone suppression of cellular toxicity of Huntingtin is independent of polyglutamine aggregation
    Zhou, H
    Li, SH
    Li, XJ
    JOURNAL OF BIOLOGICAL CHEMISTRY, 2001, 276 (51) : 48417 - 48424
  • [10] A bivalent Huntingtin binding peptide suppresses polyglutamine aggregation and pathogenesis in Drosophila
    Kazantsev, A
    Walker, HA
    Slepko, N
    Bear, JE
    Preisinger, E
    Steffan, JS
    Zhu, YZ
    Gertler, FB
    Housman, DE
    Marsh, JL
    Thompson, LM
    NATURE GENETICS, 2002, 30 (04) : 367 - 376
12345