Multi-Material Poly(Lactic Acid) Scaffold Fabricated Via Fused Deposition Modeling and Direct Hydroxyapatite Injection as Spacers in Laminoplasty

被引:12
|
作者
Syuhada, Ghifari [1 ]
Ramandita, Ghiska [2 ,4 ]
Rahyussalim, A. J. [3 ]
Whulanza, Yudan [1 ,4 ]
机构
[1] Univ Indonesia, Fac Engn, Dept Mech Engn, Kampus UI, Depok 16424, Indonesia
[2] Univ Indonesia, Fac Engn, Dept Met & Mat Engn, Kampus UI, Depok 16424, Indonesia
[3] Univ Indonesia, Cipto Mangunkusumo Hosp, Fac Med, Dept Orthoped & Traumatol, Jl Salemba Raya 6, Jakarta 10430, Indonesia
[4] Univ Indonesia, Res Ctr Biomed Engn, Kampus UI, Depok 16424, Indonesia
来源
2ND BIOMEDICAL ENGINEERINGS RECENT PROGRESS IN BIOMATERIALS, DRUGS DEVELOPMENT, AND MEDICAL DEVICES | 2018年 / 1933卷
关键词
additive manufacturing; Polylactic acid; hydroxyapatite/alginate; cervical laminoplasty; MECHANICAL-PROPERTIES;
D O I
10.1063/1.5023942
中图分类号
Q81 [生物工程学(生物技术)]; Q93 [微生物学];
学科分类号
071005 ; 0836 ; 090102 ; 100705 ;
摘要
Nowadays, additive manufacturing method has been used extensively to realize any product with specific attributes rather than the conventional subtractive manufacturing method. For instance, the additive manufacturing has enable us to construct a product layer-by-layer by successively depositing several materials in one session and one platform. This paper studied the properties of a 3D printed scaffold fabricated through Poly(Lactic-acid) (PLA) deposition modelling in combination with injectable hydroxyapatite (HA)/alginate as cell carrier. The scaffold was designed to serve as a spacer in cervical laminoplasty. Therefore, a series of test were conducted to elaborate the mechanical property, porosity and in-vitro toxicity testing. The results showed that the method is reliable to fabricate the scaffold as desired although the toxicity test needs more confirmation.
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页数:8
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