Role of D-dimer testing in severe pelvic inflammatory disease: a new usable marker to assess the need for fertility-impairing surgery?

被引:9
作者
Franchi, Laura [1 ]
Patrelli, Tito Silvio [1 ]
Berretta, Roberto [1 ]
Rolla, Martino [1 ]
Gizzo, Salvatore [1 ]
Gramellini, Dandolo [1 ]
Modena, Alberto Bacchi [1 ]
Nardelli, Giovanni Battista [1 ]
机构
[1] Univ Parma, Dept Maternal & Child Hlth, OB GYN Unit, I-43100 Parma, Italy
关键词
Pelvic inflammatory disease; D-dimer; tubo-ovarian abscess/salpingitis/salpingooophoritis/pelviperitonitis/pyosalpinx; acute/chronic genital infections; destructive/conservative surgery; clinical management; infertility; inflammatory-induced coagulation/fibrinolysis; C-REACTIVE PROTEIN; COAGULATION; DIAGNOSIS; SEPSIS;
D O I
10.1016/j.fertnstert.2010.03.080
中图分类号
R71 [妇产科学];
学科分类号
100211 ;
摘要
Pelvic inflammatory disease (PID), like many other inflammatory diseases, can be characterized by an inflammation-induced activation of the coagulation cascade, resulting in the production of D-dimers. In this study it is demonstrated how high levels of D-dimers, assayed at the time of hospitalization, are encountered in patients diagnosed with PID and how the levels of this parameter are significantly higher in patients, which due to the severity of the disease, needed surgical treatment. Therefore the D-dimer is shown to be an important parameter to be considered in the therapeutic counseling of severe forms of PID. (Fertil Steril (R) 2010;94:2372-5. (C) 2010 by American Society for Reproductive Medicine.)
引用
收藏
页码:2372 / 2375
页数:4
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