Mobilizing Parkinson's Disease: The Future of Exercise

被引:108
作者
Ellis, Terry [1 ]
Rochester, Lynn [2 ,3 ]
机构
[1] Boston Univ, Coll Hlth & Rehabil Sci, Sargent Coll, Ctr Neurorehabil, 635 Commonwealth Ave, Boston, MA 02215 USA
[2] Newcastle Univ, Inst Neurosci, Newcastle Upon Tyne, Tyne & Wear, England
[3] Newcastle Upon Tyne Hosp NHS Fdn Trust, Newcastle Upon Tyne, Tyne & Wear, England
关键词
Parkinson's disease; exercise; rehabilitation; disease modification;
D O I
10.3233/JPD-181489
中图分类号
Q189 [神经科学];
学科分类号
071006 ;
摘要
Exercise is increasingly recognized as an important element in the treatment of Parkinson's disease but what is exercise targeting? What accounts for the benefits observed in Parkinson's disease? Is exercise disease modifying? Several modes of exercise have been studied in various doses across a heterogeneous Parkinson's population. Yet more clarity is needed as to who benefits most and when, from what type of exercise and at which intensity. In this paper, we briefly review the state of the art in key areas and speculate on the likely state of research in each area in the next 20 years. Key areas relate to: (1) the physiological benefits of exercise with respect to disease modification; (2) the best type of exercise; (3) the optimal intensity of exercise; and (4) implementation strategies to increase exercise uptake. A better understanding of these concepts would allow for a more effective, personalized approach, rather than the current "one size fits all" and could most likely confer greater benefits.
引用
收藏
页码:S95 / S100
页数:6
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