5-aminolevulinic acid-based photodynamic therapy associated with Itraconazole successfully treated a case of chromoblastomycosis

被引：8
|
作者：
Yang, Weijiang [1 ]
Zhang, Wentao [1 ]
Luo, Jiefu [1 ]
Chen, Jinyi [1 ]
Tan, Yang [1 ]
Lei, Xia [1 ]
机构：
[1] Army Med Univ, Daping Hosp, Dept Dermatol, Chongqing 400042, Peoples R China
来源：
PHOTODIAGNOSIS AND PHOTODYNAMIC THERAPY | 2020年 / 29卷
基金：
中国国家自然科学基金;
关键词：
Chromoblastomycosis; Photodynamic therapy; Itraconazole; FONSECAEA-MONOPHORA;
D O I：
10.1016/j.pdpdt.2019.101589
中图分类号：
R73 [肿瘤学];
学科分类号：
100214 ;
摘要：
Chromoblastomycosis (CBM) is a prevalent implantation fungal infection. Patients with CBM show chronic granulomatous hyperplasia with ulcers and exudation. It may cause incapacity for labor in some severe clinical forms and it is often refractory to antifungal therapies. There is no optimal treatment. Here we report a case of a 71-year-old male farmer with refractory CBM who was successfully treated with 5-aminolevulinic acid-based photodynamic therapy (ALA-PDT) and Itraconazole in 2 months. Clinical cure was achieved with no obvious side effects.
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页数：3
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