Evaluation and management of acute menorrhagia in women with and without underlying bleeding disorders: consensus from an international expert panel

被引:81
作者
James, Andra H. [1 ]
Kouides, Peter A. [2 ]
Abdul-Kadir, Rezan [3 ]
Dietrich, Jennifer E. [4 ]
Edlund, Mans [5 ]
Federici, Augusto B. [6 ]
Halimeh, Susan
Kamphuisen, Pieter Willem [7 ]
Lee, Christine A. [8 ]
Martinez-Perez, Oscar [9 ]
McLintock, Claire [10 ]
Peyvandi, Flora [11 ]
Philipp, Claire [12 ]
Wilkinson, Jeffrey
Winikoff, Rochelle [13 ]
机构
[1] Duke Univ, Med Ctr, Womens Hemostasis & Thrombosis Clin, Durham, NC 27708 USA
[2] Rochester Gen Hosp, Mary M Gooley Hemophilia Treatment Ctr, Rochester, NY 14621 USA
[3] Royal Free Hosp, Dept Obstet & Gynaecol, London NW3 2QG, England
[4] Baylor Coll Med, Dept Obstet & Gynecol, Div Pediat & Adolescent Gynecol, Houston, TX 77030 USA
[5] Danderyds Univ Hosp, Dept Obstet & & Gynecol, Stockholm, Sweden
[6] Univ Milan, Div Hematol & Transfus Med, Luigi Sacco Univ Hosp, Dept Internal Med, Milan, Italy
[7] Univ Amsterdam, Acad Med Ctr, Dept Vasc Med, NL-1105 AZ Amsterdam, Netherlands
[8] Univ London, London, England
[9] Fdn Jimenez Diaz Hosp, Dept Obstet & Gynecol, Madrid, Spain
[10] Auckland City Hosp, Dept OB GYN, Auckland, New Zealand
[11] IRCCS Maggiore Policlin Hosp, Angelo Bianchi Bonomi Haemophilia Thrombosis Ctr, Dept Diag & Treatment Coagulopathies, Mangiagalli & Regina Elena Fdn, Milan, Italy
[12] Univ Med & Dent New Jersey, Robert Wood Johnson Med Sch, Dept Med, Div Hematol, New Brunswick, NJ 08903 USA
[13] CHU St Justine, Hemophilia Treatment Ctr, Montreal, PQ, Canada
关键词
Acute menorrhagia; Bleeding disorder; Hemostasis management; Consensus; Coagulation factor; VON-WILLEBRAND-DISEASE; UTERINE ARTERY EMBOLIZATION; RECOMBINANT FACTOR VIIA; TRANEXAMIC ACID; BLOOD-LOSS; DESMOPRESSIN; DEFICIENCY; HEMORRHAGE; PREVALENCE; THROMBOCYTOPENIA;
D O I
10.1016/j.ejogrb.2011.04.025
中图分类号
R71 [妇产科学];
学科分类号
100211 ;
摘要
Acute menorrhagia is a common gynecological disorder. Prevalence is high among women with inherited bleeding disorders and recent guidance for optimal management is lacking. Following a comprehensive review of the literature, an international expert panel in obstetrics, gynecology and hematology reached consensus on recommendations regarding the management of acute menorrhagia in women without a diagnosed bleeding disorder, as well as in patients with von Willebrand disease, platelet function disorders and other rare hemostatic disorders. The causes and predictors of acute menorrhagia are discussed and special consideration is given for the treatment of women on anticoagulation therapy. This review and accompanying recommendations will provide guidance for healthcare practitioners in the emergency management of acute menorrhagia. (C) 2011 Elsevier Ireland Ltd. All rights reserved.
引用
收藏
页码:124 / 134
页数:11
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