Ruthenium-catalyzed [2+2+2] cycloaddition of three different alkynes

被引：30

作者：

Ura, Y

Sato, Y

Tsujita, H

Kondo, T

Imachi, M

Mitsudo, TA ^{[1
]}

机构：

[1] Kyoto Univ, Grad Sch Engn, Dept Energy & Hydrocarbon Chem, Nishikyo Ku, Kyoto 6158510, Japan

[2] Bruker Biospin KK, Tsukuba, Ibaraki 3050051, Japan

来源：

JOURNAL OF MOLECULAR CATALYSIS A-CHEMICAL | 2005年 / 239卷 / 1-2期

关键词：

ruthenium; 2+2+2] cycloaddition; alkynes; o-phthalates; molar ratio;

D O I：

10.1016/j.molcata.2005.06.009

中图分类号：

O64 [物理化学（理论化学）、化学物理学];

学科分类号：

070304 ; 081704 ;

摘要：

A chemoselective, [2 + 2 + 2] cycloaddition of an internal alkyne, a terminal alkyne and dimethyl acetylenedicarboxylate was efficiently catalyzed by Cp*RuCl(cod) to give trisubstituted o-phthalates in good yield. lt is critical to control the molar ratio of the three substrates to achieve high chemoselectivity, and regioselectivity of the products is sensitively influenced by the bulkiness of substituents on the internal alkyne. (c) 2005 Elsevier B.V. All rights reserved.

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收藏

页码：166 / 171

页数：6

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