Stainless steel surface biofunctionalization with PMMA-bioglass coatings: compositional, electrochemical corrosion studies and microbiological assay

被引:22
作者
Floroian, L. [1 ]
Samoila, C. [2 ]
Badea, M. [3 ]
Munteanu, D. [2 ]
Ristoscu, C. [4 ]
Sima, F. [4 ]
Negut, I. [4 ,5 ]
Chifiriuc, M. C. [6 ]
Mihailescu, I. N. [4 ]
机构
[1] Transilvania Univ Brasov, Fac Elect Engn & Comp Sci, Brasov 500036, Romania
[2] Transilvania Univ Brasov, Fac Mat Sci & Engn, Brasov 500036, Romania
[3] Transilvania Univ Brasov, Fac Med, Brasov 500036, Romania
[4] Natl Inst Laser Plasma & Radiat Phys, Magurele 77125, Ilfov, Romania
[5] Univ Bucharest, Fac Phys, Magurele 077125, Ilfov, Romania
[6] Univ Bucharest, Fac Biol, Dept Microbiol, Bucharest 060101, Romania
关键词
SIMULATED BODY-FLUID; BIOACTIVE GLASS; LASER DEPOSITION; METAL RELEASE; THIN-FILMS; TI ALLOYS; RESISTANCE; TITANIUM; BIOCOMPATIBILITY; POLYMERS;
D O I
10.1007/s10856-015-5527-y
中图分类号
R318 [生物医学工程];
学科分类号
0831 ;
摘要
A solution is proposed to surpass the inconvenience caused by the corrosion of stainless steel implants in human body fluids by protection with thin films of bioactive glasses or with composite polymer-bioactive glass nanostructures. Our option was to apply thin film deposition by matrix-assisted pulsed laser evaporation (MAPLE) which, to the difference to other laser or plasma techniques insures the protection of a more delicate material (a polymer in our case) against degradation or irreversible damage. The coatings composition, modification and corrosion resistance were investigated by FTIR and electrochemical techniques, under conditions which simulate their biological interaction with the human body. Mechanical testing demonstrates the adhesion, durability and resistance to fracture of the coatings. The coatings biocompatibility was assessed by in vitro studies and by flow cytometry. Our results support the unrestricted usage of coated stainless steel as a cheap alternative for human implants manufacture. They will be more accessible for lower prices in comparison with the majority present day fabrication of implants using Ti or Ti alloys.
引用
收藏
页数:14
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