Fluorescence in situ hybridization confirms the presence of Merkel cell polyomavirus in chronic lymphocytic leukemia cells

被引:28
作者
Haugg, Anke Maria [1 ]
Speel, Ernst-Jan Maria [2 ]
Pantulu, Naga Deepa [3 ]
Pallasch, Christian [4 ]
Kurz, Anna Kordelia [5 ]
Kvasnicka, Hans Michael [6 ]
Cathomas, Gieri [7 ]
Wendtner, Clemens-Martin [4 ]
zur Hausen, Axel [1 ]
机构
[1] Maastricht UMC, Dept Pathol, GROW Sch Oncol & Dev Biol, NL-6229 HX Maastricht, Netherlands
[2] Maastricht UMC, Dept Pathol & Mol Cell Biol, GROW Sch Oncol & Dev Biol, NL-6229 HX Maastricht, Netherlands
[3] Univ Hosp Freiburg, Inst Pathol, Freiburg, Germany
[4] Univ Hosp Cologne, Dept Internal Med 1, Cologne, Germany
[5] Univ Hosp Aachen, Dept Internal Med 4, Aachen, Germany
[6] Univ Frankfurt Klinikum, Senckenberg Inst Pathol, D-6000 Frankfurt, Germany
[7] Kantonales Inst Pathol, Liestal, Switzerland
关键词
CARCINOMAS; DELETION; HPV;
D O I
10.1182/blood-2011-03-339895
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
引用
收藏
页码:5776 / 5777
页数:4
相关论文
共 5 条
[1]   Marked differences in survival rate between smokers and nonsmokers with HPV 16-associated tonsillar carcinomas [J].
Hafkamp, Harriet C. ;
Manni, J. J. ;
Haesvoets, A. ;
Voogd, A. C. ;
Schepers, M. ;
Bot, F. J. ;
Hopman, A. H. N. ;
Ramaekers, F. C. S. ;
Speel, Ernst-Jan M. .
INTERNATIONAL JOURNAL OF CANCER, 2008, 122 (12) :2656-2664
[2]   HPV in situ hybridization:: impact of different protocols on the detection of integrated HPV [J].
Hopman, AHN ;
Kamps, MA ;
Smedts, F ;
Speel, EJM ;
Herrington, CS ;
Ramaekers, FCS .
INTERNATIONAL JOURNAL OF CANCER, 2005, 115 (03) :419-428
[3]   Frequent detection of Merkel cell polyomavirus in human Merkel cell carcinomas and identification of a unique deletion in the VP1 gene [J].
Kassem, Ahmad ;
Schoepflin, Anja ;
Diaz, Carlos ;
Weyers, Wolfgang ;
Stickeler, Elmar ;
Werner, Martin ;
zur Hausen, Axel .
CANCER RESEARCH, 2008, 68 (13) :5009-5013
[4]   Detection of a novel truncating Merkel cell polyomavirus large T antigen deletion in chronic lymphocytic leukemia cells [J].
Pantulu, N. Deepa ;
Pallasch, Christian P. ;
Kurz, Anna Kordelia ;
Kassem, Ahmad ;
Frenzel, Lukas ;
Sodenkamp, Sebastian ;
Kvasnicka, Hans Michael ;
Wendtner, Clemens M. ;
zur Hausen, Axel .
BLOOD, 2010, 116 (24) :5280-5284
[5]   T antigen mutations are a human tumor-specific signature for Merkel cell polyomavirus [J].
Shuda, Masahiro ;
Feng, Huichen ;
Kwun, Hyun Jin ;
Rosen, Steven T. ;
Gjoerup, Ole ;
Moore, Patrick S. ;
Chang, Yuan .
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2008, 105 (42) :16272-16277