Successful secukinumab treatment of active bullous pemphigoid and chronic severe psoriasis: a case report

被引：20

作者：

Yun, Jenny S. W. ^{[1
]}

Scardamaglia, Laura ^{[1
,2
]}

Tan, Chin-Guan ^{[3
]}

McCormack, Christopher J. ^{[4
]}

机构：

[1] Royal Melbourne Hosp, Dermatol Dept, Parkville, Vic, Australia

[2] Univ Melbourne, Dept Med, Parkville, Vic, Australia

[3] Melbourne Pathol, Anat Pathol, Collingwood, Vic, Australia

[4] Peter MacCallum Canc Ctr, Dept Surg Oncol, Melbourne, Vic, Australia

来源：

AUSTRALASIAN JOURNAL OF DERMATOLOGY | 2022年 / 63卷 / 02期

关键词：

bullous pemphigoid; immunobullous; interleukin-17; monoclonal antibody; psoriasis;

D O I：

10.1111/ajd.13803

中图分类号：

R75 [皮肤病学与性病学];

学科分类号：

100206 ;

摘要：

Since the concurrence of bullous pemphigoid (BP) and psoriasis was first reported in 1929, an increasing number of studies has been published to analyse their relationship in recent years. However, the pathogenesis of the concurrence is not yet well understood, and the coexistence of the two conditions imposes a difficult therapeutic challenge. This case report demonstrates the first case of secukinumab achieving a dramatic clinical improvement of both chronic psoriasis and active BP.

引用

页码：E155 / E158

页数：4

共 10 条

[1] Development of bullous pemphigoid during secukinumab treatment for psoriasis [J].

Ho, Po-Han ;

Tsai, Tsen-Fang .

JOURNAL OF DERMATOLOGY, 2017, 44 (09) :e220-e221

[2] Bullous pemphigoid associated with psoriasis showing marked neutrophilic infiltrates [J].

Inamura, Emi ;

Tsujiwaki, Masumi ;

Ujiie, Hideyuki ;

Nishie, Wataru ;

Hata, Hiroo ;

Shimizu, Hiroshi ;

Iwata, Hiroaki .

JOURNAL DER DEUTSCHEN DERMATOLOGISCHEN GESELLSCHAFT, 2021, 19 (01) :105-108

[3] Secukinumab decreased circulating anti-BP180-NC16a autoantibodies in a patient with coexisting psoriasis vulgaris and bullous pemphigoid [J].

Kamata, Masahiro ;

Asano, Yoshihide ;

Shida, Rino ;

Maeda, Narumi ;

Yoshizaki, Ayumi ;

Miyagaki, Tomomitsu ;

Kawashima, Tomohiko ;

Tada, Yayoi ;

Sato, Shinichi .

JOURNAL OF DERMATOLOGY, 2019, 46 (06) :E216-E217

[4] Practical Direct Immunofluorescence [J].

Kim, Randie H. ;

Brinster, Nooshin K. .

AMERICAN JOURNAL OF DERMATOPATHOLOGY, 2020, 42 (02) :75-85

[5] The Bidirectional Association Between Bullous Pemphigoid and Psoriasis: A Population-Based Cohort Study [J].

Kridin, Khalaf ;

Ludwig, Ralf J. ;

Schonmann, Yochai ;

Damiani, Giovanni ;

Cohen, Arnon D. .

FRONTIERS IN MEDICINE, 2020, 7

[6] Innate Immune Cell-Produced IL-17 Sustains Inflammation in Bullous Pemphigoid [J].

Le Jan, Sebastien ;

Plee, Julie ;

Vallerand, David ;

Dupont, Aurelie ;

Delanez, Elodie ;

Durlach, Anne ;

Jackson, Patricia L. ;

Blalock, J. Edwin ;

Bernard, Philippe ;

Antonicelli, Frank .

JOURNAL OF INVESTIGATIVE DERMATOLOGY, 2014, 134 (12) :2908-2917

[7] Secukinumab, a human anti-interleukin-17A monoclonal antibody, in patients with psoriatic arthritis (FUTURE 2): a randomised, double-blind, placebo-controlled, phase 3 trial [J].

McInnes, Iain B. ;

Mease, Philip J. ;

Kirkham, Bruce ;

Kavanaugh, Arthur ;

Ritchlin, Christopher T. ;

Rahman, Proton ;

Van der Heijde, Desiree ;

Landewe, Robert ;

Conaghan, Philip G. ;

Gottlieb, Alice B. ;

Richards, Hanno ;

Pricop, Luminita ;

Ligozio, Gregory ;

Patekar, Manmath ;

Mpofu, Shephard .

LANCET, 2015, 386 (9999) :1137-1146

[8] Bullous pemphigoid during ustekinumab therapy in a psoriatic patient [J].

Onsun, Nahide ;

Sallahoglu, Kadriye ;

Dizman, Didem ;

Su, Ozlem ;

Tosuner, Zeynep .

EUROPEAN JOURNAL OF DERMATOLOGY, 2017, 27 (01) :81-82

[9] Association between bullous pemphigoid and psoriasis: Systematic review and meta-analysis of case-control studies [J].

Phan, Kevin ;

Goyal, Sourabh ;

Murrell, Dedee F. .

AUSTRALASIAN JOURNAL OF DERMATOLOGY, 2019, 60 (01) :23-28

[10] Concomitant psoriasis and bullous pemphigoid: coincidence or pathogenic relationship? [J].

Wilczek, Agnes ;

Sticherling, Michael .

INTERNATIONAL JOURNAL OF DERMATOLOGY, 2006, 45 (11) :1353-1357

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