REPuter: the manifold applications of repeat analysis on a genomic scale

被引：1911

作者：

Kurtz, S

Choudhuri, JV

Ohlebusch, E

Schleiermacher, C

Stoye, J

Giegerich, R

机构：

[1] Univ Bielefeld, Fac Technol, D-33501 Bielefeld, Germany

[2] Artemis Pharmaceut, D-51063 Cologne, Germany

[3] Max Planck Inst Mol Genet, Dept Computat Mol Biol, D-14195 Berlin, Germany

来源：

NUCLEIC ACIDS RESEARCH | 2001年 / 29卷 / 22期

关键词：

D O I：

10.1093/nar/29.22.4633

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

The repetitive structure of genomic DNA holds many, secrets to be discovered. A systematic study of repetitive DNA on a genomic or inter-genomic scale: requires extensive algorithmic support. The REPuter program described herein was designed to serve as a fundamental tool in such studies. Efficient and complete detection of various types of repeats is provided together with an evaluation of significance and interactive visualization. This article circumscribes the wide scope of repeat analysis using applications in five different areas of sequence analysis: checking fragment assemblies, searching for low copy repeats, finding unique: sequences, comparing gene structures and mapping of cDNA/EST sequences.

引用

页码：4633 / 4642

页数：10

共 26 条

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