Visible-Light-Induced Acylative Coupling of Benzoic Acid Derivatives with Alkenes to Dihydrochalcones

被引：8

作者：

Fan, Xiaodong ^{[1
]}

Sun, Xinhui ^{[1
]}

Ji, Mengmeng ^{[1
]}

Tong, Huixin ^{[1
]}

Zhang, Weiya ^{[1
]}

Sun, Zhizhong ^{[1
]}

Chu, Wenyi ^{[1
]}

机构：

[1] Heilongjiang Univ, Sch Chem & Mat Sci, Harbin 150080, Heilongjiang, Peoples R China

来源：

ORGANIC LETTERS | 2022年 / 24卷 / 40期

基金：

黑龙江省自然科学基金;

关键词：

AROMATIC CARBOXYLIC-ACIDS; ACYL RADICALS; STRUCTURAL CONTROL; GENERATION; POLYMERIZATION;

D O I：

10.1021/acs.orglett.2c02538

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

A strategy was developed for the visible-lightinduced photocatalytic synthesis of dihydrochalcone via the deoxygenation and coupling of benzoic acid derivatives with alkenes using diphenyl sulfide as the O-transfer reagent. Under mild photoredox conditions, a series of dihydrochalcone derivatives were produced in moderate to good yields. A mechanism for the visiblelight-induced free-radical coupling was proposed on the basis of the control experiments. The protocol provides a new strategy the generation of acyl radicals from carboxylic acids and the synthesis of dihydrochalcones.

引用

页码：7271 / 7275

页数：5

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