Automated Detection of Sleep Apnea-Hypopnea Events Based on 60 GHz Frequency-Modulated Continuous-Wave Radar Using Convolutional Recurrent Neural Networks: A Preliminary Report of a Prospective Cohort Study

被引:17
作者
Choi, Jae Won [1 ]
Kim, Dong Hyun [2 ]
Koo, Dae Lim [3 ]
Park, Yangmi [3 ]
Nam, Hyunwoo [3 ]
Lee, Ji Hyun [2 ]
Kim, Hyo Jin [2 ]
Hong, Seung-No [4 ]
Jang, Gwangsoo [5 ]
Lim, Sungmook [5 ]
Kim, Baekhyun [5 ]
机构
[1] Armed Forces Yangju Hosp, Dept Radiol, Yangju 11429, South Korea
[2] Seoul Natl Univ, Seoul Metropolitan Govt Seoul Natl Univ, Dept Radiol, Boramae Med Ctr,Coll Med, Seoul 07061, South Korea
[3] Seoul Natl Univ, Seoul Metropolitan Govt Seoul Natl Univ, Dept Neurol, Boramae Med Ctr,Coll Med, Seoul 07061, South Korea
[4] Seoul Natl Univ, Seoul Metropolitan Govt Seoul Natl Univ, Dept Otorhinolaryngol Head & Neck Surg, Boramae Med Ctr,Coll Med, Seoul 07061, South Korea
[5] AU Inc, Daejeon 34141, South Korea
关键词
obstructive sleep apnea; polysomnography; radar; deep learning; convolutional recurrent neural network;
D O I
10.3390/s22197177
中图分类号
O65 [分析化学];
学科分类号
070302 ; 081704 ;
摘要
Radar is a promising non-contact sensor for overnight polysomnography (PSG), the gold standard for diagnosing obstructive sleep apnea (OSA). This preliminary study aimed to demonstrate the feasibility of the automated detection of apnea-hypopnea events for OSA diagnosis based on 60 GHz frequency-modulated continuous-wave radar using convolutional recurrent neural networks. The dataset comprised 44 participants from an ongoing OSA cohort, recruited from July 2021 to April 2022, who underwent overnight PSG with a radar sensor. All PSG recordings, including sleep and wakefulness, were included in the dataset. Model development and evaluation were based on a five-fold cross-validation. The area under the receiver operating characteristic curve for the classification of 1-min segments ranged from 0.796 to 0.859. Depending on OSA severity, the sensitivities for apnea-hypopnea events were 49.0-67.6%, and the number of false-positive detections per participant was 23.4-52.8. The estimated apnea-hypopnea index showed strong correlations (Pearson correlation coefficient = 0.805-0.949) and good to excellent agreement (intraclass correlation coefficient = 0.776-0.929) with the ground truth. There was substantial agreement between the estimated and ground truth OSA severity (kappa statistics = 0.648-0.736). The results demonstrate the potential of radar as a standalone screening tool for OSA.
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页数:15
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