2-D graphical representation of protein sequences and its application to coronavirus phylogeny

被引:38
作者
Li, Chun [1 ]
Xing, Lili [1 ]
Wang, Xin [2 ]
机构
[1] Bohai Univ, Dept Math, Jinzhou, Peoples R China
[2] Dalian Naval Acad, Dalian, Peoples R China
关键词
ALE-index; coronavirus; graphical representation; phylogeny; protein;
D O I
10.5483/BMBRep.2008.41.3.217
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
071010 ; 081704 ;
摘要
Based on a five-letter model of the 20 amino acids, we propose a new 2-D graphical representation of protein sequence. Then we transform the 2-D graphical representation into a numerical characterization that will facilitate quantitative comparisons of protein sequences. As an application, we construct the phylogenetic tree of 56 coronavirus spike proteins. The resulting tree agrees well with the established taxonomic groups.
引用
收藏
页码:217 / 222
页数:6
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