Porous graphitic carbon as a stationary phase in HPLC: Theory and applications

被引：140

作者：

Pereira, Luisa ^{[1
]}

机构：

[1] Thermo Fisher Sci, Runcorn WA7 1PR, Cheshire, England

来源：

JOURNAL OF LIQUID CHROMATOGRAPHY & RELATED TECHNOLOGIES | 2008年 / 31卷 / 11-12期

关键词：

electronic interaction chromatography; hypercarb; isomers; polar retention effect on graphite; polar solutes; retention mechanisms;

D O I：

10.1080/10826070802126429

中图分类号：

Q5 [生物化学];

学科分类号：

071010 ; 081704 ;

摘要：

This paper gives an overview of the properties and behaviour of porous graphitic carbon (PGC) as a stationary phase in HPLC. Key applications areas that illustrate the capabilities of this chromatographic material to solve problem separations are reviewed. The retention mechanisms on this stationary phase for hydrophobic and polar solutes are described. PGCs' physical and chemical properties and the development of this unique chromatographic material are discussed. Over 140 references of applications of PGC in pharmaceutical, environmental, food safety, natural products, biochemical, clinical, and chemical warfare analysis are reviewed covering a range of solute properties.

引用

页码：1687 / 1731

页数：45

共 176 条

[131]

Phillips R, 2003, LC GC EUR, P7

[132] HPLC analysis of PCBs on porous graphitic carbon: Retention behavior and gradient elution [J].

Pietrogrande, MC ;

Benvenuti, A ;

Previato, S ;

Dondi, F .

CHROMATOGRAPHIA, 2000, 52 (7-8) :425-432

[133] Microanalytical systems for separations of stratum corneum ceramides [J].

Quinton, L ;

Gaudin, K ;

Baillet, A ;

Chaminade, P .

JOURNAL OF SEPARATION SCIENCE, 2006, 29 (03) :390-398

[134] Separation and detection of the isomeric equine conjugated estrogens, equilin sulfate and Δ8,9-dehydroestrone sulfate, by liquid chromatography-electrospray-mass spectrometry using carbon-coated zirconia and porous graphitic carbon stationary phases [J].

Reepmeyer, JC ;

Brower, JF ;

Ye, HP .

JOURNAL OF CHROMATOGRAPHY A, 2005, 1083 (1-2) :42-51

[135] Sensitive MS/MS-liquid chromatography assay for simultaneous determination of tegafur, 5-fluorouracil and 5-fluorodihydrouracil in plasma [J].

Remaud, G ;

Boisdron-Celle, M ;

Morel, A ;

Gamelin, A .

JOURNAL OF CHROMATOGRAPHY B-ANALYTICAL TECHNOLOGIES IN THE BIOMEDICAL AND LIFE SCIENCES, 2005, 824 (1-2) :153-160

[136] An accurate dihydrouracil/uracil determination using improved high performance liquid chromatography method for preventing fluoropyrimidines-related toxicity in clinical practice [J].

Remaud, G ;

Boisdron-Celle, M ;

Harneline, C ;

Morel, A ;

Gamelin, E .

JOURNAL OF CHROMATOGRAPHY B-ANALYTICAL TECHNOLOGIES IN THE BIOMEDICAL AND LIFE SCIENCES, 2005, 823 (02) :98-107

[137] Limitations of porous graphitic carbon as stationary phase material in the determination of catecholamines [J].

Rinne, Sandra ;

Holm, Anders ;

Lundanes, Elsa ;

Greibrokk, Tyge .

JOURNAL OF CHROMATOGRAPHY A, 2006, 1119 (1-2) :285-293

[138] Screening of underivatized oligosaccharides extracted from the stems of Triticum aestivum using porous graphitized carbon liquid chromatography-mass spectrometry [J].

Robinson, Sarah ;

Bergstroem, Edmund ;

Seymour, Mark ;

Thomas-Oates, Jane .

ANALYTICAL CHEMISTRY, 2007, 79 (06) :2437-2445

[139] Analysis of acrylamide in cooked foods by liquid chromatography tandem mass spectrometry [J].

Rosén, J ;

Hellenäs, KE .

ANALYST, 2002, 127 (07) :880-882

[140]

Ross P, 1997, ADV CHROMATOGR, V37, P121

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